Online monitor detector for the protontherapy beam at the INFN Laboratori Nazionali del Sud-Catania

Givehchi, N.; Marchetto, F.; Attanasio, Roberto; Attili, A.; Bourhaleb, F.; Cirio, R.; Cirrone, G.A.P.; Cuttone, G.; Rosa, F. Di; Donetti, M.; Garella, Ma; Giordanengo, S.; Iliescu, S.; Rosa, A. La; Lojacono, P.A.; Nicotra, P.; Peroni, C.; Pecka, A.; Pitta, G.; Raffaele, L.; Russo, G.; Sabini, M.G.; Valastro, L.

doi:10.1016/j.nima.2006.12.047

Cited by 20 publications

(12 citation statements)

References 7 publications

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“…This could be done exploiting a multi-gap chamber [18,19,20] this device includes two or three parallel plate ionization chambers with independent anodes and cathodes separated by gaps of different thickness in order to have different charge recombination effects and therefore different charge collection efficiencies. The charge produced in the gas is proportional to the gap width.…”

Section: Detectors For Beam Control 21 Ionization Chambersmentioning

confidence: 99%

Control Of The Dose Distribution In Charged Particle Therapy

Manganaro¹,

Attili²,

Dalmasso³

et al. 2017

Proceedings of the 26th International Nuclear Physics Conference — PoS(INPC2016)

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The use of ions in radiation therapy aims at improving the selectivity of the irradiation thanks to a favourable depth-dose profile and, in case of heavy ions, to their enhanced radiobiological effect. The treatment modality employing actively scanned pencil beams provides highly conformal dose distributions but is sensitive to uncertainties in the dose calculation, delivery and measurement. During the treatment, the delivery of the beam has to be controlled in real time and monitored with high accuracy, including any effect due to patient positioning and motion. Based on the experience gained in the collaboration with the CNAO (Centro Nazionale di Adroterapia Oncologica, Pavia, Italy), this paper is intended to give an overview of recent techniques and trends for the delivery, measurement and verification of the dose distribution in charged particle therapy with scanned ion beams, focusing in particular on real time and online techniques.

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Section: Detectors For Beam Control 21 Ionization Chambersmentioning

confidence: 99%

Control Of The Dose Distribution In Charged Particle Therapy

Manganaro¹,

Attili²,

Dalmasso³

et al. 2017

Proceedings of the 26th International Nuclear Physics Conference — PoS(INPC2016)

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“…Their design is similar to other detectors successfully developed by the Torino group for different medical applications [5,6]. For safety and redundancy requirements, two independent detectors have been designed for each treatment line: they are housed in separate boxes (called BOX1 and BOX2) and are read out and processed independently during the treatment.…”

Section: Detector Descriptionmentioning

confidence: 99%

“…In order to maximize the collection efficiency, the chambers are operated with N 2 and with a electric field of about 800 V/cm, generated by polarizing the cathodes to -400 V and the anodes at the reference voltage of the front-end input (2.05 V). It was observed that in these operating conditions the collection efficiency is about 100% [6]. The read-out electronics of the detector is based on two versions of a 64-channels wide dynamic range current-to-frequency converter ASIC developed by the Torino group: the TERA06 [7,8] for the strip and pixel chambers and the TERA07 [9] for the integral chambers.…”

Section: Detector Descriptionmentioning

confidence: 99%

Design and characterization of the beam monitor detectors of the Italian National Center of Oncological Hadron-therapy (CNAO)

Giordanengo

Donetti

Garella

et al. 2013

Nuclear Instruments and Methods in Physics Research Section A:

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A new hadron-therapy facility implementing an active beam scanning technique has been developed at the italian National Center of Oncological Hadron-therapy (CNAO). This paper presents the design and the characterization of the beam monitor detectors developed for the online monitoring and control of the dose delivered during a treatment at CNAO. The detectors are based on five parallel-plate transmission ionization chambers with either a single large electrode or electrodes segmented in 128 strips (strip chambers) and 32x32 pixels (pixel chamber). The detectors are arranged in two independent boxes with an active area larger than 200 x 200 mm 2 and a total water equivalent thickness along the beam path of about 0.9 mm. A custom front-end chip with 64 channels converts the integrated ionization channels without dead-time. The detectors were tested at the clinical proton beam facility of the Paul Scherrer Institut (PSI) which implements a spot scanning technique, each spot being characterized by a predefined number of protons delivered with a pencil beam in a specified point of the irradiation field. The short-term instability was measured by delivering several identical spots in a time interval of few tenths of seconds and is found to be lower than 0.3%. The non-uniformity, measured by delivering sequences of spots in different points of the detector surface, results to be lower than 1% in the single electrode chambers and lower than 1.5% in the strip and pixel chambers, reducing to less than 0.5% and 1% respectively in the restricted 100 x 100 mm 2 central area of the detector.

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“…Most of the beam monitor detectors are based on ionization chambers [6,7] that offer several advantages in terms of simplicity, robustness and minimal perturbation of the beam. In the perspective of these emerging technologies, the chamber efficiency has to be monitored and eventually corrected for.…”

Section: Introductionmentioning

confidence: 99%

“…In this paper we present a simple and effective solution to increase by almost two orders of magnitude the input current range of an Application Specific Integrated Circuit (ASIC) which was designed by our group and used in several laboratories worldwide [6][7][8], still maintaining a good performance in terms of noise and resolution. The chip, named TERA, implements an architecture based on a charge-to-count converter and integrates 64 equal channels.…”

Section: Introductionmentioning

confidence: 99%

A simple method to increase the current range of the TERA chip in charged particle therapy applications

Cirio

Fausti

Guarachi

et al. 2015

Nuclear Instruments and Methods in Physics Research Section A:

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a b s t r a c tThe development of the next generation of accelerators for charged particle radiotherapy aims to reduce dimensions and operational complexity of the machines by engineering pulsed beams accelerators. The drawback is the increased difficulty to monitor the beam delivery. Within each pulse, instantaneous currents larger by two to three orders of magnitude than present applications are expected, which would saturate the readout of the monitor chambers. In this paper, we report of a simple method to increase by almost two orders of magnitude the current range of an Application Specific Integrated Circuit chip previously developed by our group to read out monitor ionization chambers.

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Online monitor detector for the protontherapy beam at the INFN Laboratori Nazionali del Sud-Catania

Cited by 20 publications

References 7 publications

Control Of The Dose Distribution In Charged Particle Therapy

Control Of The Dose Distribution In Charged Particle Therapy

Design and characterization of the beam monitor detectors of the Italian National Center of Oncological Hadron-therapy (CNAO)

A simple method to increase the current range of the TERA chip in charged particle therapy applications

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