“One stone, two birds”: engineering 2-D ultrathin heterostructure nanosheet BiNS@NaLnF₄ for dual-modal computed tomography/magnetic resonance imaging guided, photonic synergetic theranostics

Abstract

It will be interesting and yet challenging to design theranostic nanoplatform for the accurate diagnosis and therapeutic of diseases, a single contrast-enhanced imaging or therapeutic agent with their own unique...

Hetero-Core–Shell BiNS–Fe@Fe as a Potential Theranostic Nanoplatform for Multimodal Imaging-Guided Simultaneous Photothermal–Photodynamic and Chemodynamic Treatment

“…PDT employs a photosensitizer to induce the generation of reactive oxygen species (ROS) after light irradiation, and these species damage the cell structures to kill cells. , However, photosensitizers, such as Ce6 and ICG with high PDT effects, have a constant excitation wavelength, poor stability, and easily undergo disintegration upon irradiation with light, , leading to the decrease of ROS generation and application restriction. Meanwhile, the tumor microenvironment limits the ROS generation, which implies that higher therapeutic efficiencies are required, and a better therapeutic effect is greatly related to the generation of ROS.…”

Recent Advances of Bismuth Halide Based Nanomaterials for Photocatalytic Antibacterial and Photodynamic Therapy

“…After irradiation with a 980 nm laser, BiNS@NaLnF 4 displays high efficiency for PDT tumor ablation due to abundant ROS induced by the increased utilization of electrons/holes and excellent up‐conversion efficiency from 980 nm light to visible light. [ 39 ] Also, a new type of upconversion nanoparticles (UCNPs) integrated with bismuth oxyhalide (BiOCl) sheets were designed for achieving excellent antitumor efficiency under NIR light irradiation. [ 40 ] During the process, the UCNPs can convert NIR light into UV/vis region emissions, which facilitates the generation of ROS to destroy tumor cells.…”

“…BiNS@NaLnF 4 with special heterojunction enhanced the utilization of electron/hole and promotes the generation of ROS under visible light illumination, further expanding the therapeutic effect. [ 47 ] Also, Jiang prepared two different morphologies of hollow flower‐like BiOI (h‐BiOI) and bulk BiOI (b‐BiOI) through a facile solvothermal method. h‐BiOI displayed a more positive VB compared to that of b‐BiOI, indicating h‐BiOI with much higher oxidation ability, which causes superior antibacterial activity LED light irradiation.…”

“…Two different procedures could be used to achieve nanomaterials with different morphologies because of the efficient use of water. Reproduced with permission [47]. Copyright 2020, Royal Society of Chemistry.…”

Recent developments in bismuth oxyhalide-based functional nanomaterials for biomedical applications

“…BiOX nanomaterials can be roughly divided into four categories based on the effect of different modifications, including the addition of nanocarbon materials to promote electron–hole separation, 93,95–99 polymers to benefit biocompatibility, 40,51,100–106 biomolecules to improve targeting, 107,108 and photosensitizers to enhance light absorption. 109–114…”