On the Interaction between 1D Materials and Living Cells

Abstract

One-dimensional (1D) materials allow for cutting-edge applications in biology, such as single-cell bioelectronics investigations, stimulation of the cellular membrane or the cytosol, cellular capture, tissue regeneration, antibacterial action, traction force investigation, and cellular lysis among others. The extraordinary development of this research field in the last ten years has been promoted by the possibility to engineer new classes of biointerfaces that integrate 1D materials as tools to trigger reconfigurable stimuli/probes at the sub-cellular resolution, mimicking the in vivo protein fibres organization of the extracellular matrix. After a brief overview of the theoretical models relevant for a quantitative description of the 1D material/cell interface, this work offers an unprecedented review of 1D nano- and microscale materials (inorganic, organic, biomolecular) explored so far in this vibrant research field, highlighting their emerging biological applications. The correlation between each 1D material chemistry and the resulting biological response is investigated, allowing to emphasize the advantages and the issues that each class presents. Finally, current challenges and future perspectives are discussed.

A Critical Review on Polymeric Biomaterials for Biomedical Applications

“…Apart from the discussed materials, such as polymeric films, sheets, 3D sponges, and hydrogels, there are other classes of materials, namely 1D and 0D materials. If a material is confined in two directions, such as wires and tubes with a diameter less than 100 nm, it is usually defined as a 1D nanomaterial [ 126 ]. Likewise, if the material is confined in all the three dimensions and shows almost spherical shape line dots, micelles with a diameter smaller than 100 nm, then it is called a 0D nanomaterial [ 127 ].…”

Frictional behavior of one-dimensional materials: an experimental perspective

“…and advanced material innovation 26,27 to groundbreaking advancements in biomedical research. [28][29][30][31][32][33][34] It is vital to underscore that the design, manufacturing, and utilization of these devices are intricately linked to a deep understanding of their surface frictional behavior, as it profoundly inuences their performance across various domains.…”

Tailoring the Surface Properties of Micro/Nanofibers Using 0D, 1D, 2D, and 3D Nanostructures: A Review on Post‐Modification Methods

“…1D structures present the length several times greater than width and encompass nanotubes and metallic nanowires, nanobelts, nanofibers, nanorods [ 37,38 ] as well as macromolecular structures as silk, DNA, and peptides. [ 39 ] 2D nanomaterials [ 40,41 ] present one dimension at the nanoscale, and encompass nanodiscs, nanoplates, and nanosheets, and typical examples include graphene oxide (GO), reduced graphene oxide (rGO), transition metal chalcogenides and dichalcogenides, clays, boron nitride, montmorillonite (MMT), and their derivates, with most common applications in the fields of sensors, catalysts, and adsorbents. 3D nanomaterials are those structures synthesized from 0D, 1D, and 2D building blocks, in which the shape reaches a micrometric dimension, yet preserving an internal nanostructure.…”