On-Line Preconcentration Method Using Normal Stacking Mode and Dynamic pH Junction for the Quality Control of Herbal Medicines Containing Related Phenolic Compounds

Acosta, Gimena; Arce, Silvia; Ortega, Claudia; Martínez, Luis D.; Gómez, María R.

doi:10.2174/15734110113090990018

Cited by 3 publications

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“…To surmount the challenge of low concentration sensitivity in CZE, sample stacking is often used as a practical online preconcentration approach (Yin et al, 2011;Chen et al, 2018a). Several sample stacking approaches have been extensively utilized, including the normal stacking mode (NSM) (Acosta et al, 2014) used in FASS (Kitagawa et al, 2013), pH-mediated stacking (Kong et al, 2017), and LVSS (Kitagawa et al, 2017). Yu et al noted that LVSS is ideal for detecting trace amounts of materials in complex sample matrices of TCM, with ng/mL detection limits (Yu et al, 2017).…”

Section: Large Volume Sample Stacking (Lvss)mentioning

confidence: 99%

Advances and strategies for capillary electrophoresis in the characterization of traditional Chinese medicine: A review of the past decade (2011–2021)

Shamsi

Patel²

2023

Front. Anal. Sci.

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While traditional Chinese medicine (TCM) is considered a valuable resource for drug discovery and form a potential basis for drug development, they also carry substantial safety risks due to adverse drug reactions and a lack of understanding of their mechanisms of action. However, due to their highly complex composition, valid analytical methodologies for analyzing TCMs must be developed and promoted. An extensive search of published research and review of scientific papers implies that the increased efficiency and sensitivity of capillary electrophoresis (CE) has attracted much research attention. This review provides an in-depth assessment of CE applications for TCM analysis published in the open literature in the last decade (2011–2021). Our survey findings showed that capillary zone electrophoresis (CZE) with ultraviolet (UV) detection is a capillary electromigration technique frequently utilized for the efficient separation, identification, and quantitation of various active components in highly complex matrices. Different extraction methods, modifiers to the background electrolyte, preconcentration techniques, and mass spectrometry (MS) detectors are used to enhance CE separation selectivity and TCM sensitivity.

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Section: Large Volume Sample Stacking (Lvss)mentioning

confidence: 99%

Advances and strategies for capillary electrophoresis in the characterization of traditional Chinese medicine: A review of the past decade (2011–2021)

Shamsi

Patel²

2023

Front. Anal. Sci.

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Recent advances in enhancing the sensitivity of electrophoresis and electrochromatography in capillaries and microchips (2012–2014)

et al. 2015

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One of the most cited limitations of capillary (and microchip) electrophoresis is the poor sensitivity. This review continues to update this series of biannual reviews, first published in Electrophoresis in 2007, on developments in the field of on-line/in-line concentration methods, covering the period July 2012-July 2014. It includes developments in the field of stacking, covering all methods from field-amplified sample stacking and large-volume sample stacking, through to ITP, dynamic pH junction, and sweeping. Attention is also given to on-line or in-line extraction methods that have been used for electrophoresis.

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Recent progress of sample stacking in capillary electrophoresis (2014–2016)

et al. 2016

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The term "sample stacking" comprises a relatively broad spectrum of techniques that already form an almost inherent part of the methodology of CZE. Their principles are different but the effect is the same: concentration of a diluted analyte into a narrow zone and considerable increase of the method sensitivity. This review brings a survey of papers on electrophoretic sample stacking published approximately since the second quarter of 2014 till the first quarter of 2016. It is organized according to the principles of the stacking methods and includes chapters aimed at the concentration adjustment principle (Kohlrausch stacking), techniques based on pH changes, micellar methods, and other stacking techniques. Not reviewed are papers on transient ITP that are covered by another review in this issue.

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On-Line Preconcentration Method Using Normal Stacking Mode and Dynamic pH Junction for the Quality Control of Herbal Medicines Containing Related Phenolic Compounds

Cited by 3 publications

References 0 publications

Advances and strategies for capillary electrophoresis in the characterization of traditional Chinese medicine: A review of the past decade (2011–2021)

Advances and strategies for capillary electrophoresis in the characterization of traditional Chinese medicine: A review of the past decade (2011–2021)

Recent advances in enhancing the sensitivity of electrophoresis and electrochromatography in capillaries and microchips (2012–2014)

Recent progress of sample stacking in capillary electrophoresis (2014–2016)

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