Omphalocele, Extrophy of Cloaca, Imperforate Anus and Spine Abnormalities – Oeis Complex : A Rare Case Report

Jyothi, Uram Aruna; Ramakrishna, Baddukonda Appala; Vandana, Kalwaje Eshwara

doi:10.14260/jemds/2015/1299

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Congenital Malformations1

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2022

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“…Although OEIS is sporadic in nature with no obvious aetiology, in some cases associated chromosomal aberrations have been reported [6]. OEIS complex has been reported in siblings from different pregnancies [3].…”

Section: Congenital Malformationsmentioning

confidence: 99%

A Rare Case of Genital Malformation with Omphalocele, Exstrophy of Bladder, Imperforate Anus and Spinal Defect Complex-Autopsy Findings

Mamatha

Yelikar

Deshpande

et al. 2017

JCDR

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Omphalocele, Exstrophy of cloaca, Imperforate anus and Spinal defects (OEIS) is a severe manifestation of exstrophy-epispadias sequence with a combination of defects including OEIS. It results from improper closure of anterior abdominal wall and defective development of cloaca and urogenital septum due to defect in blastogenesis during the 4 th week of gestation. Identification of this complex is important through foetal autopsy as this condition can recur in siblings. Prenatal diagnosis also helps to prevent foetal death with appropriate management in the less severe cases. In severe cases, termination of pregnancy is considered. A primigravida with 28 weeks of gestation had delivered a live baby with multiple congenital anomalies; baby died after 10 minutes. These anomalies were grouped under OEIS complex.

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Section: Congenital Malformationsmentioning

confidence: 99%