Olfactory bulbus volume and olfactory sulcus depth in migraine patients: an MRI evaluation

Abstract

OB volume values were lower in migraine patients. When osmophobia was present, the OB volume was lower than that of the non-osmophobia migraine patients. Olfactory function monitoring with olfactory tests and olfactory volume monitoring on MRI can be recommended for all migraine patients to diagnose olfactory dysfunction earlier, especially those with osmophobia. Because their OB volume values were detected as lower than those of the migraine patients without osmophobia, it may be thought that blood flow changes and osmophobia may affect the olfactory bulb volume shrinkage in migraine patients.

Quantitative analysis of healthy olfactory sulcus depth, olfactory tract length and olfactory bulb volume in the paediatric population: a magnetic resonance study

“…OBv and OSd measurements have been used to structurally evaluate the effect of olfactory system in many patients such as isolated congenital anosmia, chronic sinusitis related olfactory dysfunction, post-traumatic, post-infective olfactory dysfunction, epilepsy, migraine, multiple sclerosis, and chemotherapy-related conditions in children [7,8,19]. Studies have shown that olfactory structural elements are affected in many of the aforementioned diseases.…”

Olfactory bulb volume and olfactory sulcus depth in patients with Behçet's disease

“…Subjects were excluded from the study if there was a history of trauma or surgery, sinonasal tumour, sinonasal infection, sinonasal polyposis, cerebrospinal fluid leakage, marked nasal septal deformity, marked facial deformity, multiple sclerosis, epilepsy, or Parkinson's disease 13 …”

“…Fat-suppressed T2-weighted images in the coronal plane (repetition time/echo time = 6557/100 ms, field of view = 220 × 175 mm and matrix = 224 × 165 mm) were obtained using 5 mm slice thickness and 1 mm intersection gap. The measurements for standard olfactory bulb volume (Figure 1) and olfactory sulcus depth (Figure 2) were taken from coronal T2-weighted images 13 – 15 . All MRI scans were obtained on the same scanner using the same protocol for measurement.…”

“…From anterior to posterior screening, the olfactory bulb can be clearly seen. The olfactory bulb surface was measured manually (in mm 2 ) using an electronic cursor, and the volume was calculated in mm 3 by multiplying this value by the slice thickness 13 – 15 …”

“…A perpendicular line was then drawn from this tangent line to the deepest point of the olfactory sulcus. The depth of this line provided the olfactory sulcus depth (in mm) 13 – 15 …”