Ocular Inflammatory Myofibroblastic Tumor in the Left Eye with Phthisis Right Eye: A Rare Occurrence in a Child

Shah, Sangeeta; Badhu, Badri Prasad; Lavaju, Poonam; Pradhan, Anju

doi:10.1155/2015/281528

Cited by 3 publications

(3 citation statements)

References 14 publications

(28 reference statements)

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“…There is also a tenuous relationship with vasculitis, inferior vena caval thrombosis, and infections with mycobacterium avium-intracellulare complex, Epstein-Barr Virus, actinomycetes, and mycoplasma. 5,11 MRI studies of our patient showed low signal intensity on T1-weighted images and high signal intensity on T2-weighted images, reported only in 36% to 60% of cases. 13 This expression was not seen in our patient.…”

Section: Discussionmentioning

confidence: 46%

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Inflammatory Myofibroblastic Tumor—A Case Report

Lau¹,

Ahmad²,

Farhad³

et al. 2016

US Ophthalmic Review

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Inflammatory myofibroblastic tumors (IMTs) are rarely reported, benign tumors. They are uncommon in the ocular structures. A four-year-old girl presented to us with bilateral proptosis. Subsequent radiologic and histopathologic investigations proved it to be bilateral IMT. This case report is being presented because of its rarity and some of the unique features of the condition seen in our patient. Case ReportA four-year-old, apparently healthy girl presented to Queen Elizabeth Hospital, Kota Kinabalu two years ago, with a gradually progressive proptosis, lagophthalmos, and watering from her right eye for the past eight months, as noted by her mother. There was no blurring of vision, diplopia, pain, or redness noted. There was no history of trauma, nor symptoms suggestive of malignancy, thyroid abnormalities, connective tissue disease, or infection. She was well and active at home. There was also no family history of malignancy reported.Examination of the child revealed an active girl with no features of dysmorphism. The visual acuities were 6/6 in both eyes. The conjunctivae in both eyes were mildly injected. The rest of the anterior, as well as posterior, segments were normal bilaterally. She was noted to have bilateral non-axial proptosis, which was worse on the right eye. The right eye was deviated downwards and inwards. Exophthalmometer measurements at 95 mm were 18 mm on the right eye and 16 mm on the left eye. No lagophthalmos or exposure keratopathy were present.Her extraocular movements were normal. There was no relative afferent pupillary defect noted (Figures 1 and 2). AbstractThis case report highlights a 4-year old child with recurrent bilateral proptosis. Investigations revealed the presence of inflammatory myofibroblastic tumors in both eyes. These are rarely reported benign tumors. Our case showed unusual features such as orbital involvement, bony erosion and response to corticosteroids. KeywordsGranuloma, plasma cell, orbital diseases, orbital neoplasms Disclosure: Lindfay Laura Lau, Syed Shoeb Ahmad, Anis Farhad, and Shuaibah Abdul Ghani have nothing to declare in relation to this article. No funding was received in the publication of this article.Compliance with Ethics: All procedures were followed in accordance with the responsible committee on human experimentation and with the Helsinki Declaration of 1975 and subsequent revisions, and informed consent was received from the parent/guardian of the patient involved in this case study.

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Section: Discussionmentioning

confidence: 46%

“…The overall prognosis, however, is favorable. 9,11,15 Orbital involvement with IMT, especially bilateral, as seen in our patient, is extremely rare. It may present as extraocular muscle enlargement, as well as intraconal or extraconal masses.…”

Section: Discussionmentioning

confidence: 56%

Inflammatory Myofibroblastic Tumor—A Case Report

Lau¹,

Ahmad²,

Farhad³

et al. 2016

US Ophthalmic Review

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“…There is a paucity of literature on ocular morbidities in fellow eyes of patients with phthisis bulbi with which to make comparisons, especially as some data are based on pathological studies of surgical eye specimens. 6 – 8 However, Kashyap et al, 10 reported findings of retinoblastoma in fellow eyes of 15 (83.3%) of their patients and Shah et al, 19 reported a case of myofibroblastic tumour in the fellow eye of a patient with phthisis bulbi. Tan et al, 11 also reported the presence of penetrating eye injuries in eight (12.5%) fellow eyes and retinal detachment in three (4.7%) fellow eyes of patients with phthisis bulbi due to sympathetic ophthalmitis.…”

Section: Discussionmentioning

confidence: 99%

Distribution of phthisis bulbi and status of fellow eyes at a tertiary eye-care centre in Nigeria: a ten-year review

et al. 2021

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Background: Phthisis bulbi is an irreversible cause of visual loss with insufficient evidence about its aetiology and status of patients’ fellow eyes. Objectives: To identify the distribution of patients with phthisis bulbi and determine the status of their fellow eyes at Obafemi Awolowo University Teaching Hospitals Complex, Ile-Ife, Nigeria. Methods: We analysed data retrospectively retrieved from medical records of patients diagnosed with phthisis bulbi at in- itial clinic visit from January 2008 to December 2017. Information abstracted included biodata, laterality of phthisical eye, duration and aetiology of phthisis bulbi, visual acuity, and morbidities present in fellow eyes. Results: Seventy-nine patients presented with unilateral phthisis bulbi. The mean age was 51±21.2 years and forty (50.6%) were males. The commonest aetiologies of phthisis bulbi were trauma 37 (46.8%), infection 17 (21.5%) and uveitis/inflam- mation 11 (13.9%). Seventy (88.6%) patients had morbidities in their fellow eye such as glaucoma 26 (32.9%), refractive errors 23 (29.1%) and cataract 22 (27.9%). Forty (50.6%) patients were either visually impaired or blind in their fellow eye (p=0.001). Conclusion: The commonest cause of phthisis bulbi was trauma. Approximately nine out of ten patients had ocular mor- bidities in their fellow eye. A thorough follow-up of patients with phthisis bulbi is recommended. Keywords: Fellow eye; Nigeria; ocular trauma; distribution; phthisis bulbi.

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A Rare Presentation of Inflammatory Myofibroblastic Tumor in the Nasolabial Fold

Alshammari

Alzamami

Ashoor

et al. 2019

Case Reports in Otolaryngology

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Inflammatory myofibroblastic tumor (IMT) is a benign lesion that occurs most frequently in the soft tissues and viscera. In the head and neck region, the tumor has been reported to occur in the orbit, tongue, nasopharynx, larynx, and paranasal sinuses and the central nervous system. Despite being a benign lesion, it exhibits infiltrative and destructive behaviours, making histopathological examination necessary to confirm the diagnosis. We report the case of a 38-year-old female presented with a right nasolabial fold mass, which was confirmed histologically to be an IMT. Surgical excision of the mass was achieved through a sublabial approach with an uneventful postoperative period. To the best of our knowledge, this is the first reported case of an IMT in the nasolabial fold.

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Ocular Inflammatory Myofibroblastic Tumor in the Left Eye with Phthisis Right Eye: A Rare Occurrence in a Child

Cited by 3 publications

References 14 publications

Inflammatory Myofibroblastic Tumor—A Case Report

Inflammatory Myofibroblastic Tumor—A Case Report

Distribution of phthisis bulbi and status of fellow eyes at a tertiary eye-care centre in Nigeria: a ten-year review

A Rare Presentation of Inflammatory Myofibroblastic Tumor in the Nasolabial Fold

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