Occupational Chemical-Induced Hearing Loss

Fuente, Adrián; McPherson, Bradley

doi:10.5772/33852

Cited by 6 publications

(18 citation statements)

References 57 publications

(56 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The first observed greater hearing loss in 61.5% of the group occupationally exposed to OS mixture and noise; and the second reported five times more risk of hearing loss in those occupationally exposed to OS mixtures with xylene and noise, and 20 times more risk of hearing loss in workers exposed to noise and estireno, toluene and n-hexane, toluene mixtures (2005). In these studies the hearing loss was greater in high frequencies (3)(4)(5)(6)(7)(8).…”

Section: Discussionmentioning

confidence: 89%

Ototoxicity and neurotoxicity from exposure to a mixture of organic solvents and noise, a case report

Velasco-Reyna¹,

Torres-Flores²,

Rojo-Ramírez³

et al. 2019

IJCR

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 89%

Ototoxicity and neurotoxicity from exposure to a mixture of organic solvents and noise, a case report

Velasco-Reyna¹,

Torres-Flores²,

Rojo-Ramírez³

et al. 2019

IJCR

View full text Add to dashboard Cite

“…Research findings indicate that the vapour particles of solvents are inhaled by workers, which are then absorbed via the respiratory tract (Johnson & Morata, 2010 ). They can also be absorbed through the skin or exposed wound tissue, after which they translocate into the blood stream and travel through the body and affect cells where they interact with tissue that causes dysfunction in the body and certain organs (Baker, Smith, & Landrigan, 1985 , Fuente & McPherson, 2012 ; Unlu, Kesici, Basturk, Kos, & Yilmaz, 2014 ; Yah, Iyuke, & Simate, 2011 ). In addition, once solvents are absorbed into the body via inhalation, the body’s metabolic system transforms the solvents into components that are present in blood and then excreted in urine.…”

Section: Discussionmentioning

confidence: 99%

“…Research has shown that solvents then poison the hair cells, which results in the membranous structures becoming disorganised and causing hair cell death (Campo et al, 2007 ). In terms of specific OHC damage, the third row of OHCs is thought to be most vulnerable as it is closest to the stria vascularis (Campo et al, 2007 ) after which the first and second rows are affected (Fuente & McPherson, 2012 ; Fuente, McPherson, & Hickson, 2013 ). Furthermore, solvents affect the OHCs in a specific area, that is, the middle turn area, where middle frequencies are located (Choi & Kim, 2014 ; Sulkowski et al, 2002 ) and this is different from NIHL where the higher frequencies are generally affected (Johnson & Morata, 2010 ; Tochetto, Quevedo, and Siqueira, 2013 ).…”

Section: Discussionmentioning

confidence: 99%

“…Solvents are liquids that are used to dissolve substances, are colourless, have strong odours and have been noted in recent literature to induce auditory pathology. For the purpose of the review, the term ‘Solvent-Induced Hearing Loss’ (SIHL) will be used, as solvents are ototoxic agents that cause hearing loss (Fuente & McPherson, 2006 , 2012 ).…”

Section: Introductionmentioning

confidence: 99%

“…Three literature reviews were conducted previously regarding the combined effects of solvents and noise on auditory function. Fuente and McPherson ( 2012 ) provided a detailed discussion on hearing loss related to various solvents and their interaction with noise. Key findings of the study indicated that there are detrimental effects associated with solvents on the peripheral and central auditory system.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

The effects of combined exposure of solvents and noise on auditory function – A systematic review and meta-analysis

Nakhooda

Sartorius

Govender

2019

South African Journal of Communication Disorders

View full text Add to dashboard Cite

Background Chemical substances can negatively affect the auditory system. Chemical substances alone or combined with high-level noise have recently become a major concern as a cause of occupational hearing loss. Objective To assess the combined effect of solvents and noise versus solvents only, or noise only, on the auditory function of workers. Method Published articles which included noise and/or solvent exposure or combined effects of solvents and noise, studies conducted on human beings only and the use of audiological tests on participants. Results Thirteen papers were eligible for inclusion. The participants’ ages ranged from 18 to 68 years. Results revealed that 24.5% presented with hearing loss as a result of noise exposure only; 18% presented with hearing loss owing to solvent exposure only; and a total of 43.3% presented with hearing loss owing to combined noise and solvent exposure. Furthermore, the prevalence of hearing loss in the noise and solvent group was significantly ( p < 0.001) higher than the other groups in 10 out of the 13 studies analysed, with a pooled odds ratio (OR) of 2.754. Of the 178 participants (total of all participants exposed to solvents), a total of 32 participants presented with auditory pathology as a result of exposure to solvents only. There was a significantly higher pooled odds of hearing loss in noise and solvent-exposed group compared to solvent-only group (pooled OR = 2.15, 95% CI: 1.24–3.72, p = 0.006). Conclusion The findings revealed significantly higher odds of acquiring hearing loss when workers were exposed to a combination of solvents and noise as opposed to solvents only, motivating for its inclusion into hearing conservation programmes.

show abstract

Audiological Tests Used in the Evaluation of the Effects of Solvents on the Human Auditory System: A Mixed Methods Review

et al. 2023

Self Cite

View full text Add to dashboard Cite

This study aimed to scope the literature, identify knowledge gaps, appraise results, and synthesize the evidence on the audiological evaluation of workers exposed to solvents. We searched Medline, PubMed, Embase, CINAHL, and NIOSHTIC-2 up to March 22, 2021. Using Covidence, two authors independently assessed study eligibility, risk of bias, and extracted data. National Institute of Health Quality Assessment Tools was used in the quality evaluation of included studies; the Downs and Black checklist was used to assess the risk of bias. Of 454 located references, 37 were included. Twenty-five tests were studied: two tests to measure hearing thresholds, one test to measure word recognition in quiet, six electroacoustic procedures, four electrophysiological tests, and twelve behavioral tests to assess auditory processing skills. Two studies used the Amsterdam Inventory for Auditory Disability and Handicap. The quality of individual studies was mostly considered moderate, but the overall quality of evidence was considered low. The discrepancies between studies and differences in the methodologies/outcomes prevent recommending a specific test battery to assess the auditory effects of occupational solvents. Decisions on audiological tests for patients with a history of solvent exposures require the integration of the most current research evidence with clinical expertise and stakeholder perspectives.

show abstract

Occupational Chemical-Induced Hearing Loss

Cited by 6 publications

References 57 publications

Ototoxicity and neurotoxicity from exposure to a mixture of organic solvents and noise, a case report

Ototoxicity and neurotoxicity from exposure to a mixture of organic solvents and noise, a case report

The effects of combined exposure of solvents and noise on auditory function – A systematic review and meta-analysis

Audiological Tests Used in the Evaluation of the Effects of Solvents on the Human Auditory System: A Mixed Methods Review

Contact Info

Product

Resources

About