Occupation and risk of lymphoid and myeloid leukaemia in the European Prospective Investigation into Cancer and Nutrition (EPIC)

Abstract

Our findings suggest a possible role of occupational exposures in the development of both lymphoid and myeloid leukaemia. Exposure to benzene seemed to be associated with both acute and chronic myeloid leukaemia.

Medical History, Lifestyle, Family History, and Occupational Risk Factors for Adult Acute Lymphocytic Leukemia: The InterLymph Non-Hodgkin Lymphoma Subtypes Project

“…Despite the small numbers (four cases and 191 controls), this association was observed for B-cell ALL (OR = 4.38, 95% CI = 1.41 to 13.6), but not for T-cell ALL. Previous studies have also reported an increased risk of NHL in workers in textile-related occupations (23)(24)(25) and of acute myeloid leukemia in those in shoe or other leather goods industries (26). However, there have been no previous reports linking textile and sewing/embroidery occupations with risk of adult ALL.…”

Use of job-exposure matrices to estimate occupational exposure to pesticides: A review

“…[111][112][113] In particular, the ad hoc JEMs created by P Stewart 15,16,[101][102][103][104][105] are a hybrid between a job-exposure matrix and expert raters' assessment. They were based both on the literature and industrial hygienists' experience.…”

“…112,113 Various pesticide definitions were used in these matrices. They were sometimes considered as a generic group, 91,94,99,100,[106][107][108][109][110]112 were classified in functional groups (H/F/I), [14][15][16]92,93,96,[101][102][103][104][105]111,113 or were identified at the active ingredient level. 95,98 The occupations concerned were detailed very precisely in some studies.…”

“…95,98 The occupations concerned were detailed very precisely in some studies. 14,15,94,98,109 Occupational data (lifetime occupational history, current or longest held occupation) were self-reported by study participants in most studies, more or less precisely, [14][15][16][93][94][95][96][97][98][99][100][102][103][104][105][106][107][108][109][110][111]113,114 or were obtained from databases. 91,92,101 In some studies, the information was complemented by job-specific questionnaires.…”

“…The health effects studied were mainly cancers, 15,[91][92][93][94]98,99,[101][102][103][106][107][108]111 and the study design was mostly case-control. [91][92][93][94][96][97][98][99][100][101][102][103][104][105][106][106][107][108][109][110] However, other outcomes were studied such as neurological diseases, 14,96,97,100,109,110 birth outcomes 95,104,105 and respiratory diseases.…”