Observações clínicas e laboratoriais em cães com cinomose nervosa

Tudury, Eduardo Alberto; Árias, Mônica Vicky Bahr; Bracarense, Ana Paula Frederico Rodrigues Loureiro; Megid, Jane; Júnior, Rubens Ferreira Dias

doi:10.1590/s0103-84781997000200010

Cited by 15 publications

(16 citation statements)

References 5 publications

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“…Such protein components are nearly exclusively represented by albumin, despite small amounts of globulins can be found (Braund, 1994). However, when CNS is damaged, the protein levels can increase in dogs with viral encephalitis (distemper), toxoplasmosis, bacterial meningitis, brain or spinal cord abscess, as well as in noninflammatory conditions, such as seizure states and uremia (Tudury et al, 1997). The increase in protein content might occur as a result of local production of protein in the central nervous system, although concurrent increase in total CSF albumin and in the ratio of CSF albumin to serum albumin (albumin quota) suggests impairment of the blood-brain barrier and leakage of plasma albumin, because it is solely produced by the liver (Delahunta, 1983;Feldman, 1989).…”

Section: Introductionmentioning

confidence: 99%

Evaluation of electrophoretic profile and albumin quota in the cerebrospinal fluid of dogs with distemper showing or not neurvous signs

Gama

Nishimori

Sobreira

et al. 2007

Arq. Bras. Med. Vet. Zootec.

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Evaluation of electrophoretic profile and albumin quota in the cerebrospinal ABSTRACTThe electrophoretic profile of cerebrospinal fluid proteins and albumin quota was studied in healthy dogs and dogs with distemper in either nervous or non-nervous phases. Cerebrospinal fluid (CSF) samples from 30 dogs were collected by puncture of the cisterna magna. The total protein content, the albumin quota, and the electrophoretic fraction of CSF proteins in agarose gel plates were evaluated. Results were similar in healthy dogs and dogs with distemper and no nervous signs, but were significantly increased in the group of dogs with distemper showing nervous signs. The study of CSF protein profile proved useful and contributed significantly on the detection of central nervous system disorders and damages to the blood-brain barrier during the nervous phase of distemper.

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Section: Introductionmentioning

confidence: 99%

Evaluation of electrophoretic profile and albumin quota in the cerebrospinal fluid of dogs with distemper showing or not neurvous signs

Gama

Nishimori

Sobreira

et al. 2007

Arq. Bras. Med. Vet. Zootec.

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“…However, when the nervous system is affected, the protein levels may be increased, particularly in cases of encephalitis, as reported by SORJONEM (1987) andTUDURY et al (1997) in dogs with canine distemper, toxoplasmosis, meningitis, spinal cord or brain abscessation, and also in non-inflammatory conditions characterized by convulsion and uremia. .…”

Section: Introductionmentioning

confidence: 70%

Physical-chemical analysis of the cerebrospinal fluid of healthy dogs submitted to different storage periods and temperatures

2006

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“…Sonne et al (2009) verified 44.4% of the animals with pneumonia and Kubo et al (2007) reported that the main finding in 100 dogs with distemper was pneumonia. Also Tudury et al (1997) reported 12.34% of dogs with distemper showing bronchopneumonia.…”

Section: Discussionmentioning

confidence: 95%

Anatomopathological changes in canine distemper seropositive dogs and virus detection in sinoatrial nodes

et al. 2020

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Canine distemper is a viral disease that affects several systems on dogs, among them, the cardiovascular system. The aim of this study was to identify canine distemper virus (CDV) in the sinoatrial node (SAN) of dogs serologically positive for distemper by Polymerase Chain Reaction preceded by reverse transcription (RT-PCR), and to analyze gross and microscopic changes of distemper in the heart and other tissues. SAN and tissue fragments were collected from 17 serologically positive dead animals, necropsied from October 2015 to December 2016. In the heart, right heart dilatation was observed in 13 dogs (76.47%) and left concentric hypertrophy in two dogs (11.76%). Microscopically, lymphocytic myocarditis was observed in four (23.53%) dogs and 41.18% presented viral inclusion corpuscles of CDV in the bladder epithelium. Only one (5.88%) dog presented a 319 bp target fragment for distemper virus using primers CDV 1 and CDV 2 at the sinoatrial node. In conclusion, CDV can be located in the sinoatrial node of naturally infected dogs, as demonstrated in this study by the RT-PCR technique, reinforcing the hypothesis that CDV is capable of causing inflammatory lesions in the sinoatrial node of this species. Macroscopic and microscopic cardiac changes are frequently observed in dogs with distemper, mainly cardiac dilatation and myocarditis. Viral inclusions of CDV in bladder epithelial cells are an important microscopic finding for the diagnosis of distemper.

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Observações clínicas e laboratoriais em cães com cinomose nervosa

Abstract: RESUMO Em 81 cães com sinais clínicos, lesões histológicas e corpúsculos de inclusão no sistema nervoso central

Cited by 15 publications

References 5 publications

Evaluation of electrophoretic profile and albumin quota in the cerebrospinal fluid of dogs with distemper showing or not neurvous signs

Evaluation of electrophoretic profile and albumin quota in the cerebrospinal fluid of dogs with distemper showing or not neurvous signs

Physical-chemical analysis of the cerebrospinal fluid of healthy dogs submitted to different storage periods and temperatures

Anatomopathological changes in canine distemper seropositive dogs and virus detection in sinoatrial nodes

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