Several hundred obese children have been referred to us as having Fr\l=o"\hlich's syndrome, or dystrophia adiposogenitalis. These patients were presumed to have pituitary disease or a combination of pituitary with thyroid involvement. Approximately 80 of this number1 have been studied thoroughly from the point of view of physical development (sexual and mensurational) (fundi and visual fields), and complete laboratory studies were made, including roentgenographic examination of the head (sella turcica), wrist and knee, and basal metabolism, blood cholesterol and sugar tolerance tests. In addition, we have used a roent-Downloaded From: http://archpedi.jamanetwork.com/ by a University of California -San Diego User on 06/09/2015