2015
DOI: 10.1590/1983-084x/12_145
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O extrato bruto hidroalcoólico das folhas de Piper caldense C. DC. na redução do consumo de álcool em ratos.

Abstract: RESUMO:A investigação de plantas medicinais como recurso terapêutico para combater o alcoolismo ainda é muito insipiente com poucas espécies investigadas. No presente trabalho avaliamos o efeito do extrato hidroalcoólico das folhas da planta Piper caldense C. DC. com relação ao consumo de álcool e também a sua potencialidade ansiolítica. Foram utilizados ratos Wistar machos, os quais foram divididos em grupos controle (solução fisiológica) e tratado (extrato da planta nas doses de 25, 50 e 150 mg/kg, e diazepa… Show more

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Cited by 4 publications
(1 citation statement)
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“…The amount of 100 g of dry and powdered leaves was soaked in a mixture of 70% ethanol and 30% water for 7 days. The solution was filtered, concentrated, and freeze-dried following the method described by Pereira et al (2015) [29]. Shimadzu Prominence coupled with a diode array detector (DAD) and a mass spectrometer equipped with electrospray ionization, quadrupole analyzer, and time-of-flight in a MicrOTOF-Q III (Bruker Daltonics, Billerica, MA, USA).…”
Section: Chemicalsmentioning
confidence: 99%
“…The amount of 100 g of dry and powdered leaves was soaked in a mixture of 70% ethanol and 30% water for 7 days. The solution was filtered, concentrated, and freeze-dried following the method described by Pereira et al (2015) [29]. Shimadzu Prominence coupled with a diode array detector (DAD) and a mass spectrometer equipped with electrospray ionization, quadrupole analyzer, and time-of-flight in a MicrOTOF-Q III (Bruker Daltonics, Billerica, MA, USA).…”
Section: Chemicalsmentioning
confidence: 99%