Nutritional support for patients with COVID-19 coronavirus infection

Abstract

Prophylaxis, diagnostics and correction of nutritional status disturbances is considered as one of the main treatment methods of patients with COVID-19 infection-directed to resolve systemic inflammatory response and correction of metabolic response to a viral infection. Systemic Inflammatory Reaction (SIR) manisfestation as a result of viral infection leads to pronounced metabolic processes disturbances. The main metabolic manifestations of SIR is reflected as hypermetabolic-hypercatabolic syndrome with complex disturbances of protein, lipids and carbohydrates metabolism, increased consumption of carbohydrate-lipid reserves and breakdown of tissue proteins. Thus, adequate correction of metabolic disorders and a wholesome nutritional support, taking into account the clinical picture, severity of the disease, ongoing respiratory and intensive care therapy is an integral component in treating patients with COVID-19 infection which determines the efficiency of its treatment and reduction in mortality. Given the relevance of the problem, the authors decided that it was important to increase the COVID-19 treatment efficacy by producing guidelines based on the most fundamental provisions of the modern approach to nutritional support in critical patients with community acquired pneumonia, acute respiratory failure, ARDS, sepsis, multiple organ failure.

Medical and Social Aspects of the New Coronavirus Infection

“…The potential threat of the possibility of the avian influenza virus breaking through the biological barrier is growing, which, according to virologists, is able to destroy three-quarters of the world's population [37,43]. As a rule, for such widespread pathogens of viral infections as HIV infection, hepatitis B, coronavirus infection, herpes simplex, and for all newly emerging ones, humanity does not have direct-acting antiviral drugs, a number of insufficiently studied posed questions arise in the problem of a new coronavirus infection, including: the ability to influence the increase in the resistance of the human body without the use of drugs, often with a dubious effect of the type of immunostimulating agents [44,45]; to introduce modern nutraceuticals as a manda-tory component of patient therapy, including targeted action (medicine should not be food, but food can become medicine) [46][47][48]; tactics of health authorities regarding compliance with the calendar of immunoprophylaxis of infectious diseases against the background of an ongoing pandemic [49,50].…”

Анализ Влияния Омега-3-Полиненасыщенных Жирных Кислот На Воспаление: Патогенетические Механизмы, Эффектыи Клиническое Значение Их Применения

“…«Рецепт», 2020, том 23, № 6 Омега-3 ПНЖК способны частично ингибировать ряд аспектов воспаления, включая хемотаксис лейкоцитов, экспрессию молекулы адгезии и адгезивные взаимодействия лейкоцитов и эндотелия, выработки эйкозаноидов, таких как простагландины и лейкотриены. Некоторые исследования показали положительные результаты после энтерального применения больших доз ω-3 ПНЖК при синдроме системного воспаления (СВ) у пациентов в критических состояниях [5], при патологиях беременности и невынашивании [6], раке желудка [7]. В период неожиданной инфекционной угрозы и пандемии 2019-2020 гг.…”