Nutritional Influences in Early Life upon Obesity and Body Proportions

‘Thinfat’ phenotype in newborns

“…16 Specific nutritional deficiencies, possibly secondary to maternal under nutrition, could also render the fetus unable to lay down lean tissue mass, so energy becomes deposited as fat. 17 One of the interesting observation of the present study was contribution of genetic factors to the prevalence of 'thinfat' phenotype. This statement we make because, consanguinity was significantly associated with this phenotype (p < 0.05).…”

Overweight is gender-dependent in prenatal protein–calorie restricted adult rats acting on the blood pressure and the adverse cardiac remodeling

“…The availability of nutrients at different times during gestation, by interacting with the maternal and fetal hormonal profile, predisposes to different patterns of growth (Jackson et al, 1996). These relationships between the organ size and the function underscore one of the basic biologic compensatory properties: inherent ability to increase or decrease mass (hypertrophy or atrophy) and to alter tissue configuration in direct relationship to functional requirements (Kenchaiah and Pfeffer, 2004).…”

Global burden of obesity in 2005 and projections to 2030

“…Williamson (151) studied a nationally representative cohort of smokers and nonsmokers in the USA (1971)(1972)(1973)(1974)(1975)(1976)(1977)(1978)(1979)(1980)(1981)(1982)(1983)(1984) and found that the mean weight gain attributable to smoking cessation was 2.8kg in men and 3.8kg in (136)(137)(138).…”