Numerical solutions of population balance models in preferential crystallization

Efficient solution of a batch crystallization model with fines dissolution

“…For the size-dependent growth rate, a 1 ¼ 300 m À1 and a 2 ¼ 1 in Eq. (10). For the size-independent growth rate, a 1 ¼ 0.…”

“…Recently, new techniques were introduced to effectively utilize dissolution for producing narrow CSDs and for growing desired polymorph [7,8]. Moreover, fines dissolution was used to improve the preferential crystallization of enantiomers [9,10].…”

Application of a recent FBRM-probe model to quantify preferential crystallization of dl-threonine

“…(2)) suitable discretization schemes have to be used. There are a number of sophisticated discretization schemes available (Hu et al, 2005;Motz et al, 2002;Qamar et al, 2008Qamar et al, , 2007Qamar et al, , 2006Ramkrishna, 2000). The method of characteristics (MOC) can be easily applied when it can be assumed, as in our work, that no nucleation of the counter enantiomer takes place.…”

Preferential crystallization: Multi‐objective optimization framework

“…where, r 5 0.3947 and h 5 26.8263 are determined from experiments, 38 and the initial moments are determined using Eq. 20.…”