Application of a recent FBRM-probe model to quantify preferential crystallization of dl-threonine

Metastable zone width, crystal nucleation and growth kinetics measurement in anti-solvent crystallization of β-artemether in the mixture of ethanol and water

“…FBRM was also utilized as the tool to characterize both the nucleation and crystal growth kinetics. Czapla et al (2010) developed a FBRM model to quantify preferential crystallization of dl-threonine, the kinetic parameters of preferential crystallization were estimated based on FBRM CLD data. Trifkovic et al (2008) researched the crystallization kinetics using FBRM and CLD was directly used for parameters estimation of crystal growth kinetics using the method of moment, which was regarded as a paradigm for kinetics measurement.…”

Demulsifying water-in-oil emulsions by ethyl cellulose demulsifiers studied using focused beam reflectance measurement

“…6 and 7 collectively demonstrate the advantage of studying demulsification kinetics using FBRM: (i) quantitative on-line measurement without emulsion sampling and/or dilution, (ii) probing demulsification kinetics in real time, and (iii) understanding the extent of demulsification. A possible issue that may result in a misleading increase in the counts of smaller chords comes from the possibility of chord-splitting, where the two edges of a single particle is counted as two chords (Czapla et al, 2010;Kail et al, 2007). In our system, single water droplets in diluted bitumen are spherical and therefore there should be no geometrical edge effect.…”

Restoration of particle size distributions from fiber-optical in-line measurements in fluidized bed processes

“…The FBRM enables the in-situ detection of chord lengths distributions, originating from reflected laser light of passing particles (Ruf et al, 2000). Due to this robust functional principle the FBRM has been successfully employed in diverse measurement applications in liquid-solid systems even at high solid concentrations (Czapla et al, 2010;Heath et al, 2002, Kempkes et al, 2008Langston et al, 2001;Li and Wilkinson., 2005;Ma et al 2009). By contrast only few reports discuss the application of FBRM devices for particle sizing purposes to gas-solid fluidized beds, which can be ascribed to the vigorous fouling effects during wet granulation processes.…”