Numerical analysis of the leaflet elasticity effect on the flow in the model of a venous valve

Gataulin, Y A; Yukhnev, A D; Smirnov, S. I.; Rosukhovskiy, D A

doi:10.1088/1742-6596/1359/1/012010

Cited by 3 publications

(2 citation statements)

References 3 publications

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“…Lamé’s parameters for hyperelastic are μ = 1.0 MPa and λ = 1.5 MPa, considering modulus of elasticity E = 2.6 MPa and Poisson’s ratio ν = 0.3 [ 30 ], whereas the properties of the fluid were set as follows: the density of fluid 1055 kg m −3 (density of blood at 37 °C [ 31 , 32 ]) and the dynamic viscosity of fluid 2.78 × 10 −3 Pa·s (viscosity of blood at 37 °C). The flow velocity was 16 ± 4 cm/s, which is a typical IJV velocity in humans in the supine body position [ 33 ].…”

Section: Methodsmentioning

confidence: 99%

Results of Numerical Modeling of Blood Flow in the Internal Jugular Vein Exhibiting Different Types of Strictures

Rashid

Iqrar²,

Rashid³

et al. 2022

Diagnostics

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The clinical relevance of nozzle-like strictures in upper parts of the internal jugular veins remains unclear. This study was aimed at understanding flow disturbances caused by such stenoses. Computational fluid dynamics software, COMSOL Multiphysics, was used. Two-dimensional computational domain involved stenosis at the beginning of modeled veins, and a flexible valve downstream. The material of the venous valve was considered to be hyperelastic. In the vein models with symmetric 2-leaflets valve without upstream stenosis or with minor 30% stenosis, the flow was undisturbed. In the case of major 60% and 75% upstream stenosis, centerline velocity was positioned asymmetrically, and areas of reverse flow and flow separation developed. In the 2-leaflet models with major stenosis, vortices evoking flow asymmetry were present for the entire course of the model, while the valve leaflets were distorted by asymmetric flow. Our computational fluid dynamics modeling suggests that an impaired outflow from the brain through the internal jugular veins is likely to be primarily caused by pathological strictures in their upper parts. In addition, the jugular valve pathology can be exacerbated by strictures located in the upper segments of these veins.

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Section: Methodsmentioning

confidence: 99%

Results of Numerical Modeling of Blood Flow in the Internal Jugular Vein Exhibiting Different Types of Strictures

Rashid

Iqrar²,

Rashid³

et al. 2022

Diagnostics

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“…In some peripheral vein simulations, simplified vein models with a diameter of 3 to 5 mm are often used. [14][15][16] However, these studies focused on the condition of blood flow patency. To obtain the filling diameter of the best puncture site in the state of hemostasis, this study randomly selected 28 subjects and measured the full filling diameter of the best puncture site of the middle elbow vein in the state of hemostasis by using an ultrasound probe.…”

Section: Summary Textmentioning

confidence: 99%

Flushing effect of micro-bolus pulse injection and its potential impact on peripheral veins under hemostasis

Li,

Wang,

et al. 2023

Medicine

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To explore the feasibility of using micro-bolus pulse injection method to reduce the dilution effect of pipeline on high concentration injection, and to understand low liquid volume bolus injection based on low injection speed. Using a programmable pulse injection pump, a 25-cm – long pipeline containing water-soluble fluorescent agent was flushed using different volumes of bolus, and the time spent for the complete disappearance of the fluorescent agent was recorded to evaluate the flushing efficiency. The finite element simulation of 2-phase flow was carried out using computational fluid dynamics (CFD) technology, and the difference of shear rate and pressure distribution in the vein of pulse injection and direct injection of bolus under hemostasis was compared and simulated. Micro-bolus pulse flushing has advantages in completing perfusion imaging applications, such as small volume imaging agent injection. Compared with non-pulse injection, the effective flushing volume decreases by 49.7%, the average injection speed decreases by 56%, and the maintenance time of high shear rate is shorter when using micro-bolus pulse injection. The impact of micro-bolus pulse injection on the vein can achieve the same or even lower negative effects as other injection methods after increasing the hemostatic distance to 100 mm. In the case of bolus injection requiring high concentration and small volume, such as for radiopharmaceutical dynamic imaging, the application of micro-bolus pulse injection is an effective way to overcome the dilution phenomenon of the imaging agent in the pipeline. During hemostasis, the micro-bolus pulse injection needs to control a longer hemostasis distance to reduce the potential impact on peripheral veins.

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Fluid–structure interaction modelling of the venous valve with elastic leaflets

Tikhomolova

Gataulin

Yukhnev

et al. 2020

J. Phys.: Conf. Ser.

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The paper presents the results of a numerical study of the flow in a symmetric model of a healthy popliteal venous valve with different leaflet elasticity. The focus is on the analysis of the stagnant area under the valve leaflet. The stagnant area under the valve leaflet, as well as behind the valve, is of great practical interest to phlebologists in terms of the possibility of blood clots. The flow in the constructed simplified model of the venous valve gave good qualitative agreement with the clinical ultrasound data for a leaflet with Young modulus of 1.2 MPa.

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Numerical analysis of the leaflet elasticity effect on the flow in the model of a venous valve

Cited by 3 publications

References 3 publications

Results of Numerical Modeling of Blood Flow in the Internal Jugular Vein Exhibiting Different Types of Strictures

Results of Numerical Modeling of Blood Flow in the Internal Jugular Vein Exhibiting Different Types of Strictures

Flushing effect of micro-bolus pulse injection and its potential impact on peripheral veins under hemostasis

Fluid–structure interaction modelling of the venous valve with elastic leaflets

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