Results of Numerical Modeling of Blood Flow in the Internal Jugular Vein Exhibiting Different Types of Strictures

Rashid, Anas; Iqrar, Syed Atif; Rashid, Aiman; Simka, Marian

doi:10.3390/diagnostics12112862

Cited by 9 publications

(4 citation statements)

References 45 publications

(46 reference statements)

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“…In reality, they exhibit different levels of elasticity and movability. In our other in silico study, we demonstrated that there is a dynamic interplay between stenoses located upstream and valves located downstream, and that a relevant stenosis changes the valve geometry to the unfavorable one [46]. Thirdly, flow volume measurements using the "probes" were not very precise.…”

Section: Discussionmentioning

confidence: 78%

Numerical Modeling of Venous Outflow from the Cranial Cavity in the Supine Body Position

Simka,

Czaja,

Kawalec

et al. 2024

Applied Sciences

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The hemodynamic relevance of differently located stenoses of the internal jugular veins remains undetermined. It particularly concerns nozzle-like strictures in the upper parts of these veins and stenotic jugular valves located at the end of these veins. This study was aimed at understanding flow disturbances caused by such stenoses. The computational fluid dynamics software Flowsquare+ was used. We constructed 3-dimensional models of the venous outflow, comprising two alternative routes: the tube representing the internal jugular vein and an irregular network representing the vertebral veins. At the beginning of the tube representing the internal jugular vein, differently shaped and sized short strictures representing nozzle-like strictures were built in. At the end of this tube, differently shaped membranes representing the jugular valve were built in. With the use of computational fluid dynamics modeling, we studied how these two obstacles influenced the outflow. We found that the most relevant outflow disturbances were evoked by the nozzle-like strictures in the upper part of the internal jugular vein that were small, long, or asymmetrically positioned. Very tight stenotic valves and septum-like malformed valve were equally hemodynamically relevant. These findings suggest that both upper and lower strictures of the internal jugular vein can be of clinical significance.

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Section: Discussionmentioning

confidence: 78%

Numerical Modeling of Venous Outflow from the Cranial Cavity in the Supine Body Position

Simka,

Czaja,

Kawalec

et al. 2024

Applied Sciences

Self Cite

View full text Add to dashboard Cite

show abstract

“…Actually, they exhibit different levels of elasticity and movability. In our another in silico study, we demonstrated that there is a dynamic interplay between stenosis located upstream and the valve located downstream, and that a relevant stenosis changes the valve geometry to the unfavorable one [35]. Thirdly, flow volume measurements using the "probes" were not very precise.…”

Section: Discussionmentioning

confidence: 85%

Numerical Modeling of the Venous Outflow from the Cranial Cavity in the Supine Body Position

Simka,

Czaja,

Kawalec

et al. 2024

Preprint

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Hemodynamic relevance of differently located stenoses of the internal jugular veins remains undetermined. It particularly concerns nozzle-like strictures in the upper parts of these veins and stenotic jugular valves located at the end of this vein. This study was aimed at understanding flow disturbances caused by such stenoses. Computational fluid dynamics software, Flowsquare+, was used. We constructed 3-dimensional models of venous outflow, comprising two alternative routes: tube representing the internal jugular vein and irregular network representing the vertebral veins. At the beginning of the tube representing the internal jugular vein, differently-shaped and sized short strictures, representing nozzle-like strictures were built in. At the end of this tube, differently-shaped membranes, representing the jugular valve, were built in. With the use of computational fluid dynamics modeling, we studied how these two obstacles influenced the outflow. We found that the most relevant outflow disturbances were evoked by nozzle-like strictures in the upper part of the internal jugular vein that were either small, long or asymmetrically positioned. Very tight stenotic valves and septum-like malformed valve were equally hemodynamically relevant. These findings suggest that both upper and lower strictures of the internal jugular vein can be of clinical significance.

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“…The flows in the right and left jugular veins were considered the same and equal to half of the total flow in the superior vena cava. This simplification is justified by the scarcity of data in the literature, by the absence of consensus regarding the flow values in the right and left jugular veins [28,29] and the possible similarity of the flow values between those two veins . As a boundary condition at the outlet of the superior vena cava, the pressure curve in the right atrium was adopted from to Mynard JP, Smolich JJ (2015) [27].…”

Section: Boundary Conditionsmentioning

confidence: 99%

Dialysis flow rate in central venous catheters – A numerical analisys with experimental validation.

Gonçalves

Costa

Silva

et al. 2023

Preprint

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Despite a great number of studies regarding the favorable correlation between higher dialysis dose and the clinical efficiency of the hemodialysis treatment, the effect dialyses flow rate inside the catheter has been few investigated in the perspective of the hemodynamics modifications in central venous access for hemodialysis. This study proposes the numerical simulation and na in-vitro experimental validation of this model to assess the hemodynamic behavior and the thrombogenic potential in central venous access for hemodialysis, using different flow rates values in the central venous catheter (200, 250, 300, 350 and 400 mL/min). A mathematical model based in the Eulerian formulation was implemented in the solver subroutine to calculate the platelet lysis index (PLI). The pressure drop values obtained by numerical and experimental models were compered in order to validate the numerical model. The maximum percentage difference between those models was less than 13%. The flow rates values of 250, 300 and 350 mL/min resulted in larger recirculation zones in the flow field. It was possible to conclude that, in general, shear stresses and turbulence intensity increased in a quadratic manner with dialysis dose. The platelet lysis index increased with the dialysis flow rate and showed higher values in instants of time associated with major recirculation zones.

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Results of Numerical Modeling of Blood Flow in the Internal Jugular Vein Exhibiting Different Types of Strictures

Cited by 9 publications

References 45 publications

Numerical Modeling of Venous Outflow from the Cranial Cavity in the Supine Body Position

Numerical Modeling of Venous Outflow from the Cranial Cavity in the Supine Body Position

Numerical Modeling of the Venous Outflow from the Cranial Cavity in the Supine Body Position

Dialysis flow rate in central venous catheters – A numerical analisys with experimental validation.

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