Abstract:The structure of the reaction product from 1,3,5‐trinitrobenzene and an excess (i.e. at least four moles) of diazomethane, as found many years ago by Heinke, is shown to be a seven‐membered ring‐compound condensed with two cyclopropane rings and with one pyrazoline ring (VII). If 1,3,5‐trinitrobenzene is treated with diazomethane in a molar ratio of 1:3, no pyrazoline derivative is formed, but a hitherto unknown “tris‐methylene” derivative (VI), containing a seven‐membered ring system condensed with two cyclop… Show more
Aromatic nitro compounds can react in many ways with bases. The reaction path followed depends mainly on the degree of nitration (with a sharp jump from mononitro to di-and trinitro compounds) and the base used. Redox reactions or nucleophilic aromatic substitutions predominate with mononitro compounds, whereas Meisenheimer additions together with nucleophilic aromatic substitutions are preferred by dinitro and trinitro compounds; deprotonations are less common. The bromize in nitrobromobenzenes can be replaced by metal at low temperatures. Very weak bases generally give electron donoracceptor complexes.
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