Untitled

Okamoto, Susumu

doi:10.3136/nskkk1962.24.40

Cited by 9 publications

(2 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In the 1970s, methods to form extracted keratins into powders, films, gels, coatings, fibers, and foams were developed and published by several research groups [33,34,35]. All of these methods made use of the oxidative and reductive chemistries developed decades earlier, or variations thereof.…”

Section: History Of Keratin Biomaterialsmentioning

confidence: 99%

A Review of Keratin-Based Biomaterials for Biomedical Applications

2010

View full text Add to dashboard Cite

Advances in the extraction, purification, and characterization of keratin proteins from hair and wool fibers over the past century have led to the development of a keratin-based biomaterials platform. Like many naturally-derived biomolecules, keratins have intrinsic biological activity and biocompatibility. In addition, extracted keratins are capable of forming self-assembled structures that regulate cellular recognition and behavior. These qualities have led to the development of keratin biomaterials with applications in wound healing, drug delivery, tissue engineering, trauma and medical devices. This review discusses the history of keratin research and the advancement of keratin biomaterials for biomedical applications.

show abstract

Section: History Of Keratin Biomaterialsmentioning

confidence: 99%

A Review of Keratin-Based Biomaterials for Biomedical Applications

2010

View full text Add to dashboard Cite

show abstract

“…Keratin has been investigated as a biomaterial in various forms such as gels, films, and scaffolds since 1972 . Fibrous keratins consist of two major morphological parts: (1) the cuticle layer composed of overlapping cells that surround the cortex and (2) the inner part of the fiber (the cortex).…”

Section: Most Electrospun Polymers Used For Bone Regenerationmentioning

confidence: 99%

Electrospun biodegradable nanofibers scaffolds for bone tissue engineering

Khajavi

Abbasipour

Bahador

2015

J of Applied Polymer Sci

144

View full text Add to dashboard Cite

Many polymeric materials have been developed and introduced for bone regeneration. Especially, their nanofibrous forms are mostly applied for artificial extracellular matrices. Polymeric materials in their nanofibrous form show some potent properties such as high surface-to-volume ratio, tunable porosity, and ease of surface functionalization. Benefiting from the properties of their main polymer and additives, they can provide new opportunities for cell seeding, proliferation, and new 3D-tissue formation. This article focuses on most cited polymeric nanofibrous scaffolds fabricated by electrospinning and recent achievements. They were divided into two main categories: natural (collagen, silk, keratin, gelatin, chitosan, and alginate) and synthetic (e.g., polycaprolactone, polylactic acid, and polyglycolic acid) polymers. The role of several additives like hydroxyapatite, bone morphogenetic proteins (BMPs), tricalcium phosphate, and collagen type I in improving the adhesion, differentiation, and tissue formation of stem cells were discussed. Finally, the osteogenic capacity and ability of nanofibrous scaffolds to support the growth of clinically relevant bone tissue were briefly studied.

show abstract