Novos anticoagulantes em cuidados intensivos

Flato, Uri Adrian Prync; Buhatem, Thais; Merluzzi, Thalita; Bianco, Antonio C.

doi:10.1590/s0103-507x2011000100012

Cited by 11 publications

(26 citation statements)

References 52 publications

(41 reference statements)

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“…Schvartsman (1999); Lopes e Matheus (2012) relatam o uso do carvão ativado como um dos melhores processos de descontaminação digestiva, via oral. Em eventos hemorrágicos, para controle de sangramento, sugere-se o uso de fatores específicos de coagulação, sendo um deles o carvão ativado (FLATO et al, 2011).…”

Section: Fonte: Autores (2019)unclassified

Resíduos Agroindustriais Aplicados À Compósitos Cimentícios / Agro-Industrial Waste Applied to Cementitious Composites

Reis

Maia

Serra

et al. 2020

BJD

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Section: Fonte: Autores (2019)unclassified

Resíduos Agroindustriais Aplicados À Compósitos Cimentícios / Agro-Industrial Waste Applied to Cementitious Composites

Reis

Maia

Serra

et al. 2020

BJD

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“…Anticoagulants are used to treat blood clots during thromboembolic events which do not have specific signs and consistent symptoms (Flato et al, 2011). For example, this agents are used to prevent and treat venous thromboembolism, for stroke prevention in atrial fibrillation, embolism prevention in heart failure, and in the management of atrial fibrillation.…”

Section: Future Perspectives Novel Anticoagulant Therapiesmentioning

confidence: 99%

“…On the other hand, Direct factor Xa inhibitors (DFXaI) directly affects Factor Xa without effects on other intrinsic/extrinsic coagulation pathways. Rivaroxaban, apixaban, edoxaban, and betrixaban are in this category of anticoagulants (Flato et al, 2011).…”

Section: Future Perspectives Novel Anticoagulant Therapiesmentioning

confidence: 99%

Technology Advancements in Blood Coagulation Measurements for Point-of-Care Diagnostic Testing

Aria

Erten

Yalçın

2019

Front. Bioeng. Biotechnol.

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In recent years, blood coagulation monitoring has become crucial to diagnosing causes of hemorrhages, developing anticoagulant drugs, assessing bleeding risk in extensive surgery procedures and dialysis, and investigating the efficacy of hemostatic therapies. In this regard, advanced technologies such as microfluidics, fluorescent microscopy, electrochemical sensing, photoacoustic detection, and micro/nano electromechanical systems (MEMS/NEMS) have been employed to develop highly accurate, robust, and cost-effective point of care (POC) devices. These devices measure electrochemical, optical, and mechanical parameters of clotting blood. Which can be correlated to light transmission/scattering, electrical impedance, and viscoelastic properties. In this regard, this paper discusses the working principles of blood coagulation monitoring, physical and sensing parameters in different technologies. In addition, we discussed the recent progress in developing nanomaterials for blood coagulation detection and treatments which opens up new area of controlling and monitoring of coagulation at the same time in the future. Moreover, commercial products, future trends/challenges in blood coagulation monitoring including novel anticoagulant therapies, multiplexed sensing platforms, and the application of artificial intelligence in diagnosis and monitoring have been included.

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“…O Tempo de Protrombina ou Tempo de Atividade da Protrombina (TAP) e a Razão Normalizada Internacional (INR) são as medidas laboratoriais utilizadas para avaliar a via extrínseca da coagulação 3 . O principal objetivo é a prevenção de eventos tromboembólicos, como Trombose Venosa Profunda (TVP), com o menor risco hemorrágico.…”

Section: Introductionunclassified

Elevação da razão normalizada internacional por interação medicamentosa em paciente crítico de unidade de terapia intensiva: relato de caso

Lima¹,

Veras²,

Pinheiro³

et al. 2019

J Health Biol Sci.

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Relato de caso: o caso relatado apresenta uma paciente com uso de anticoagulantes e antimicrobianos que resultou na elevação dos valores do parâmetro de tempo de protombina e razão normalizada internacional, associados às condições hemodinâmicas. Conclusão: a interação medicamentosa foi identificada por um farmacêutico clínico e comunicada à equipe médica, que alterou a prescrição, observando-se melhora nos exames.

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Novos anticoagulantes em cuidados intensivos

Cited by 11 publications

References 52 publications

Resíduos Agroindustriais Aplicados À Compósitos Cimentícios / Agro-Industrial Waste Applied to Cementitious Composites

Resíduos Agroindustriais Aplicados À Compósitos Cimentícios / Agro-Industrial Waste Applied to Cementitious Composites

Technology Advancements in Blood Coagulation Measurements for Point-of-Care Diagnostic Testing

Elevação da razão normalizada internacional por interação medicamentosa em paciente crítico de unidade de terapia intensiva: relato de caso

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