Novel phthalocyanines containing resorcinol azo dyes; synthesis, determination of pKa values, antioxidant, antibacterial and anticancer activity

Kantar, Cihan; Akal, Hayriye; Kaya, Bülent; İslamoğlu, Fatih; Türk, Mustafa; Şaşmaz, Selami

doi:10.1016/j.jorganchem.2014.12.042

Cited by 74 publications

(27 citation statements)

References 40 publications

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“…the FIC activity results of Pcs containing resorcinol azo dyes were found to be similar to our results. In our study, compound 3 showed much higher FIC activity than the other compounds tested in both studies [27].…”

Section: Determination Of Ferrous Ion Chelating Activitymentioning

confidence: 40%

Antioxidant properties of water-soluble phthalocyanines containing quinoline5-sulfonic acid groups

Günsel¹,

Alıcı²,

Bilgiçli³

et al. 2019

Turk J Chem

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In the present study, the antioxidant properties of peripherally and nonperipherally water-soluble tetra (quinoline 5-sulfonic acid) substituted metal-free (1, 2), Zn(II) (3, 4), Co(II) (5, 6), and Mn(III)Cl (7, 8) phthalocyanine (Pc) derivatives were reported. In order to determine the antioxidant properties of the Pc compounds, three different commonly known antioxidant methods were used: DPPH (α , α-diphenylβ-picrylhydrazyl) radical scavenging, ferrous ion chelating, and reducing power assays. Compound 6 showed the best DPPH activity among the other tested compounds except for the standards. The ferrous ion chelating IC 50 value of compound 7 was nearly as good as that of the EDTA standard. The reducing power activity results indicated that the tested Pc compounds were as sensitive as standard reducing agents such as butylated hydroxytoluene and ascorbic acid. Overall, all tested compounds showed good antioxidant properties and it may be suggested that they could be used as new positive controls for reducing power assays in the future works.

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Section: Determination Of Ferrous Ion Chelating Activitymentioning

confidence: 40%

Antioxidant properties of water-soluble phthalocyanines containing quinoline5-sulfonic acid groups

Günsel¹,

Alıcı²,

Bilgiçli³

et al. 2019

Turk J Chem

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“…A typical procedure was used for the synthesis of the azo dye ligand . In a 250 mL beaker, 2 g of resorcinol was dissolved in 30 mL of 10% (w/v) NaOH solution until a clear solution was obtained.…”

Section: Methodsmentioning

confidence: 99%

Synthesis of azo‐functionalized ion‐imprinted polymeric resin for selective extraction of nickel(II) ions

Monier

Shafik

Abdel-Latif

2018

Polymer International

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“…A section of neglected tropical diseases are associated with helminths, and they are amongst the most common ones affecting the world and posing major public health threat, thus contributing to high morbidity and mortality [3,4]. e existence of few antimicrobials and anthelminthics coupled with current chemotherapy losing their efficacy calls for continuous research for new but more effective compounds in the drug discovery industry [5,6].…”

Section: Introductionmentioning

confidence: 99%

Synthesis and In Vitro Antimicrobial and Anthelminthic Evaluation of Naphtholic and Phenolic Azo Dyes

Adu

Amengor

Ibrahim

et al. 2020

Journal of Tropical Medicine

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The antimicrobial activity of 2-naphtholic and phenolic azo compounds was determined against seven microbial species, Staphylococcus aureus (ATCC 25923), Streptococcus pyrogenes (clinical), and Enterococcus faecalis (ATCC 29212), Salmonella typhi (clinical), Pseudomonas aeruginosa (ATCC 27853), Escherichia coli (ATCC 251922), and Candida albicans (ATCC 10231), using the high-throughput spot culture growth inhibition assay (HT-SPOTi). The minimum inhibitory concentrations (MIC) were determined for the active azo dyes. All the azo compounds (A1–B4) were screened for anthelmintic activity against adult Ghanaian earthworms, Hyperiodrilus spp. As part of the systematic investigation for biological activity, all the azo compounds exhibited good antimicrobial activity against the seven human pathogenic microorganisms. All the compounds exhibited anthelminthic activity against adult Ghanaian earthworms, Hyperiodrilus spp.

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Novel phthalocyanines containing resorcinol azo dyes; synthesis, determination of pKa values, antioxidant, antibacterial and anticancer activity

Cited by 74 publications

References 40 publications

Antioxidant properties of water-soluble phthalocyanines containing quinoline5-sulfonic acid groups

Antioxidant properties of water-soluble phthalocyanines containing quinoline5-sulfonic acid groups

Synthesis of azo‐functionalized ion‐imprinted polymeric resin for selective extraction of nickel(II) ions

Synthesis and In Vitro Antimicrobial and Anthelminthic Evaluation of Naphtholic and Phenolic Azo Dyes

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