Novel coronavirus disease (COVID-19): a pandemic (epidemiology, pathogenesis and potential therapeutics)

Hamid, Saima; Mir, Mohammad Yaseen; Rohela, Gulab Khan

doi:10.1016/j.nmni.2020.100679

Cited by 204 publications

(202 citation statements)

References 45 publications

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“…The transmission could happen by having close contact with confirmed positive cases with a percentage of 60.4% and without a contact with percentage of 10.9% (15). Coronavirus can be transmitted from human to human through close contact by splashes of droplets when coughing and sneezing of an infected person (10,12,(16)(17)(18) especially at close distances (19), and can spread through aerosols (16). In addition, it was also mentioned that SARS-CoV-2 can spread through the air especially in the air of rooms that have limited ventilation (19).…”

Section: Discussionmentioning

confidence: 99%

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The Impact of Ambient Air Pollution Toward Coronavirus Disease 2019 (Covid19): A Literature Review

Nasikhah

Pawitra

2020

JKL

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Introduction: WHO has announced coronavirus Disease 2019 (Covid19) as a global pandemic at the immune decline, one of which is due to chronic exposure to ambient air pollution. This literature review aims to describe the impact of ambient air pollution toward the risk of being infected by Covid19. Discussion: Covid19 can be found in a bat (host primer), and can be contagious through a person, also possible from pets. The symptoms that sufferers will perceive are fever, cough, diarrhea, myalgia, fatigue, headache, nausea, vomit, abdominal pain, loss of appetite, and some asymptomatic people. The body’s immunity affects a person’s susceptibility to Covid19 infection. The body’s immunity can be affected by ambient air pollution (with PM10, PM2,5, and O3 are the most pollutant in the air in various countries) for an extended period could be the reason for chronic illness (especially, respiratory tract) could reduce immune resistance. Furthermore, it might be happened on increasing at ACE2 activity and can cause increasing infected by Covid19. Prevention action can be done by contributing from all of the sectors at an observance in guarding, physical distancing, quarantine, and maintaining the ambient air quality in the future. Conclusion: Ambient air pollution must be considered as one effort to prevent chronic illness that can reduce immunity, which can increase the risk of being infected with Covid19. Furthermore, future studies will be carried out on ACE2 activity in people infected with Covid19 in order to get more valid results and following current conditions.

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Section: Discussionmentioning

confidence: 99%

“…Covid19 can infect humans at any age (25). However, the age of the most infected is between 35-55 years (10). In addition, many virus infections occur at an average age of 59 years with a prevalence that still tends to be high and can result a death (26).…”

Section: Discussionmentioning

confidence: 99%

The Impact of Ambient Air Pollution Toward Coronavirus Disease 2019 (Covid19): A Literature Review

Nasikhah

Pawitra

2020

JKL

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“…Furthermore, the guidelines are available on the treatment, prevention, and control of COVID-19. The guidelines also endorse ways of minimizing the fear of COVID-19 among the overall population [138]. Considering all the nonpharmaceutical measures assist the maintenance of the public outcomes of the pandemic to be in control, because of several financial reasons, the numbers are again elevating.…”

Section: Prevention and Controlmentioning

confidence: 99%

Understanding COVID-19: From Origin to Potential Therapeutics

Moazzam

Sajid

Shahid

et al. 2020

IJERPH

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Currently, a global pandemic era of public health concerns is going on with the Coronavirus Disease 2019 (COVID-19), which is caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). The first case of COVID-19 was reported from Wuhan’s Huanan seafood market in China late December 2019. Bats, pangolins, and snakes have been nominated as salient carriers of the virus. Thanks to its high pathogenicity, it can cause severe respiratory infections. Fever, dry cough, sore throat, pneumonia, septic shock, and ground-glass opacities are the foremost clinical manifestations of COVID-19. Immunocompromised patients are at high risk for COVID-19 infection and may lead to death. Scientist and government agencies around the globe are putting forward their best efforts and resources for the effective treatment of human coronavirus infections; however, neither vaccines nor antiviral drugs are available for the treatment of human coronaviruses (HCoV) infections such as SARS (severe acute respiratory syndrome), MERS (Middle Eastern respiratory syndrome), and COVID-19. Since the outbreak, a plethora of research and review articles have been published. Moreover, the mass media has bombarded the public with conflicting opinions about the pandemic. There is a dire need for accurate and reliable information concerning this pandemic. In this review, we have compiled the up to date information about the origins, evolution, epidemiology, and pathogenesis of this disease. Moreover, very few reports have addressed the clinical features and current status of treatment for COVID-19; we have adequately addressed these topics in detail in this review. Finally, a detailed account of clinical trials of vaccines and other therapeutics currently in progress has been delineated.

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“…The world is now facing the rst corona viral pandemic. [1][2][3][4] Recently discovered SARS-CoV2 causes it.…”

Section: Introductionmentioning

confidence: 99%

“…[2] The disease is named as COVID-19. [2] It ranges from asymptomatic illness to a severe form of the disease. [5][6] The death toll is considerably high, and at the present moment apart from the Russian vaccine, there is no approved medication or vaccine for prevention or cure of COVID-19 illness.…”

Section: Introductionmentioning

confidence: 99%

Selocalcitol: Scope of inhalational formulation for prevention and cure of COVID-19 illness

Kaur

Yadav

Singh

et al. 2020

Preprint

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Vitamin D has generated interest in the context of COVID-19 pandemic. Some authorities believe that it is beneficial; others think that without proven deficiency it should not be administered. The results of clinical trial are still awaited. Therefore nothing regarding the matter is conclusively known. In this context we believe that selocalcitol, a Vitamin D analogue if administered via inhalational route, has the potential to prevent SARS-CoV2 infection. The basis of this idea is presented here.

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Novel coronavirus disease (COVID-19): a pandemic (epidemiology, pathogenesis and potential therapeutics)

Cited by 204 publications

References 45 publications

The Impact of Ambient Air Pollution Toward Coronavirus Disease 2019 (Covid19): A Literature Review

The Impact of Ambient Air Pollution Toward Coronavirus Disease 2019 (Covid19): A Literature Review

Understanding COVID-19: From Origin to Potential Therapeutics

Selocalcitol: Scope of inhalational formulation for prevention and cure of COVID-19 illness

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