Novel and highly efficient lipase-catalyzed esterification of formic acid with hexanol for waste gas reutilization

Seo, Jeongbae; Shin, Minguk; Lee, Jong-Hwa; Lee, Taek; Oh, Jong‐Min; Park, Chulhwan

doi:10.1016/j.jiec.2020.10.022

Cited by 10 publications

(23 citation statements)

References 37 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…When water activity is low, insufficient water is provided to form the essential water layer around the enzyme, which negatively affects enzymatic activity. High water activity can cause an excessively thick water layer, which leads to a competition effect between esterification and hydrolysis, also resulting in inhibition of the enzymatic activity [ 4 , 12 , 13 , 15 , 21 , 29 , 30 ].…”

Section: Resultsmentioning

confidence: 99%

“…The esterification reaction can be carried out both chemically and enzymatically. However, the chemical method requires a high temperature and high pressure, which can affect the phenolic structure of flavonoids [ 4 , 11 , 12 , 13 ]. In addition, chemical esterification can produce byproducts such as isomers, owing to its low regioselectivity [ 12 , 13 , 14 , 15 ].…”

Section: Introductionmentioning

confidence: 99%

“…However, the chemical method requires a high temperature and high pressure, which can affect the phenolic structure of flavonoids [ 4 , 11 , 12 , 13 ]. In addition, chemical esterification can produce byproducts such as isomers, owing to its low regioselectivity [ 12 , 13 , 14 , 15 ]. However, in an enzymatic reaction, owing to high regioselectivity, the reaction occurs only at a specific reaction site.…”

Section: Introductionmentioning

confidence: 99%

“…However, enzymes incur a higher cost than chemical methods, are less stable, and are difficult to separate, which translate to poor process applicability. To minimize these issues, immobilized enzymes are used, which have higher stability and higher durability than free enzymes and they can be applied to various reactions and processes owing to the easy separation involved and the possibility to reuse the enzymes [ 12 , 13 , 15 , 18 , 19 ].…”

Section: Introductionmentioning

confidence: 99%

“…Lipase hydrolyzes lipids to produce fatty acids and glycerol and it catalyzes esterification and transesterification reactions under anhydrous conditions. The esterification reaction by lipase is accomplished by a ping-pong mechanism [ 4 , 12 , 13 , 15 , 20 ].…”

Section: Introductionmentioning

confidence: 99%

See 4 more Smart Citations

Improved Productivity of Naringin Oleate with Flavonoid and Fatty Acid by Efficient Enzymatic Esterification

et al. 2022

Self Cite

View full text Add to dashboard Cite

Naringin is a flavonoid found in citrus fruits. It exhibits biological activities, such as anticancer and antioxidant effects, but it suffers from low solubility and low stability in lipophilic systems. These drawbacks lead to difficulties in the commercial application of naringin, but they can be overcome through esterification. In this study, naringin oleate was synthesized by enzymatic esterification and optimal conditions for the reaction were investigated. Experiments were conducted focusing on the following parameters: enzyme type, enzyme concentration, molar ratio of naringin to oleic acid, reaction temperature, and reaction solvent. We further confirmed the degree of esterification based on the difference in the initial and the final naringin concentrations. A conversion of 93.10% was obtained under optimized conditions (Lipozyme TL IM 10 g/L, molar ratio 1:20, reaction temperature 40 °C, acetonitrile as solvent, and 48 h reaction time). Thus, naringin oleate, a high value-added material that overcomes the low hydrophobicity of naringin and enhances its performance, was obtained through esterification of naringin using oleic acid. This study presented a method for the efficient enzymatic synthesis that could ensure high conversion within a shorter reaction time compared with that required in previously reported methods.

show abstract