Nosocomial Meningitis due to<i>Streptoccus salivarius</i>Linked to the Oral Flora of an Anesthesiologist

Suy, Florence; Verhoeven, Paul; Lucht, F.; Grattard, Florence; Carricajo, Anne; Pozzetto, Bruno; Berthelot, Philippe

doi:10.1086/669517

Cited by 11 publications

(6 citation statements)

References 9 publications

(7 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“… 71 , 72 , 73 Case reports and literature reviews alert to the occurrence of cases of meningitis caused by Streptococcus salivarius , a bacterial species prevalent in normal oral flora in humans, whose source of infection was upper airway droplets of health professionals (confirmed by genotyping techniques). 74 Anesthesia professionals who perform neuraxial procedures without wearing a surgical mask, expose patients to devastating risks and infectious complications, including death. 75 …”

Section: Factors Associated With Infectious Complications In Regional...mentioning

confidence: 99%

“… 113 , 114 , 115 , 116 The time of onset of symptoms may suggest the etiologic agent. 74 It presents as a progressive disease, starting with localized back pain (most common initial symptom), local hypersensitivity, and fever and chills in the first stage; nerve root irritation and headache occur in the second stage; neurological deficits, such as muscle weakness, sensory deficits, bladder and bowel dysfunction occur in the third stage, followed by paralysis in the fourth stage. 76 , 87 , 108 Initial back pain and nerve root symptoms can remain stable for hours to weeks.…”

Section: Diagnosis and Treatment Of Regional Anesthesia-related Infec...mentioning

confidence: 99%

See 1 more Smart Citation

SBA 2020: Regional anesthesia safety recommendations update

Azi

Fonseca

Linard

2020

Brazilian Journal of Anesthesiology (English Edition)

View full text Add to dashboard Cite

Section: Factors Associated With Infectious Complications In Regional...mentioning

confidence: 99%

Section: Diagnosis and Treatment Of Regional Anesthesia-related Infec...mentioning

confidence: 99%

SBA 2020: Regional anesthesia safety recommendations update

Azi

Fonseca

Linard

2020

Brazilian Journal of Anesthesiology (English Edition)

View full text Add to dashboard Cite

“…Znani so primeri, pri katerih so s pomočjo molekularnih metod dokazali genetsko enake bakterije S. salivarius v likvorju bolnika in slini zdravstvenega delavca, kar kaže na verjeten prenos povzročitelja z neustrezno zaščitenega izvajalca posega na bolnika (9,(11)(12)(13).…”

Section: Razpravljanjeunclassified

Streptococcus salivarius kot povzročitelj iatrogenega meningitisa – predstavitev primera

2017

View full text Add to dashboard Cite

We present a case of a 28-year-old patient who underwent spinal anaesthesia for caesarean section, and developed meningitis, Streptococcus salivarius was isolated in the cerebrospinal ﬂuid. The Viridans streptococci are a part of a normal human mouth ﬂora, therefore the patient most likely developed iatrogenic meningitis due to droplet transmission of bacteria intrathecally. We discuss etiology, pathogenesis, clinical presentation, diagnostic tools, treatment and prognosis of meningitis afer intrathecal procedures and we emphasize the importance of strict aseptic technique while performing neuraxial procedures. Iatrogenic meningitis should be considered as a possible diﬀerential diagnosis in patients who present with symptoms and signs of meningitis after neuraxial blockade.

show abstract

“…Streptococcus mitis, S. oralis, and S. salivarius are associated with an initial bacteria tooth-adhesion, which can be used as a bridge to other oral microbiota members such as other streptococci and periodontopathogens (Butler et al 2017). Furthermore, there are reports of meningitis caused by S. salivarius (Falomir et al 2014, Suy et al 2013, Vignier et al 2014; whereas S. oralis and S. mitis can increase virulence factors of Candida albicans (Palma et al 2019) and cause bloodstream infections in pediatric patients (Basaranoglu et al 2019). The S. mutans is the most frequently associated microorganism with caries development, being responsible for initiated tooth demineralization acidifying microenvironment and tooth surface (Abranches et al 2018;Baker et al 2016).…”

Section: Introductionmentioning

confidence: 99%

Schinopsis brasiliensis Engl. to combat the biofilm-dependents diseases in vitro

Sette‐de‐Souza

Santana

Sousa

et al. 2020

An. Acad. Bras. Ciênc.

View full text Add to dashboard Cite

Dental caries and periodontal disease are the most prevalent of the biofilmdependent diseases. With numerous side effects on the use of chlorhexidine, the search for new safe therapeutic alternatives for microorganisms involved with these diseases increases every day. This study aimed to evaluate the antimicrobial activity and cytotoxicity of extracts made from the bark of Schinopsis brasiliensis Engl. against five oral microorganisms and analyze their phytochemical and thermal degradation profile. The liquid-liquid partition was performed with hexane, chloroform and ethyl acetate. The identification and quantification of the chemical marker was done. Antimicrobial activity was evaluated based on the minimum inhibitory concentration. The cytotoxicity was analyzed based on the hemolysing potential of the samples. The thermal degradation profile was performed by two different methods. Gallic acid was identified as the main compound of the samples and showed the highest amount in the chloroform fraction. All samples were able to inhibit the growth of the microorganisms tested and showed no cytotoxicity. The ethanol extract absorbs less heat than the fractions. All samples exhibited exothermic peak consistent with degradation of gallic acid. Based on the results, the samples used are potential candidates for use in dental formulations for biofilm control.

show abstract

Nosocomial Meningitis due toStreptoccus salivariusLinked to the Oral Flora of an Anesthesiologist

Cited by 11 publications

References 9 publications

SBA 2020: Regional anesthesia safety recommendations update

SBA 2020: Regional anesthesia safety recommendations update

Streptococcus salivarius kot povzročitelj iatrogenega meningitisa – predstavitev primera

Schinopsis brasiliensis Engl. to combat the biofilm-dependents diseases in vitro

Contact Info

Product

Resources

About