Normal weight obesity: Relationship with lipids, glycaemic status, liver enzymes and inflammation

Marques‐Vidal, Pedro; Pécoud, A; Hayoz, Daniel; Paccaud, Fred; Mooser, Vincent; Waeber, Gérard; Vollenweider, P.

doi:10.1016/j.numecd.2009.06.001

Cited by 133 publications

(116 citation statements)

References 24 publications

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“…Total body water (TBW), fat-free mass (FFM) and body fat were calculated using the equations of the apparatus. Normal-weight obesity was defined as BMI <25kg/m 2 with body fat percentage over the gender-specific tertile (20) .…”

Section: Bioimpedance Techniquementioning

confidence: 99%

Nutritional profile of asymptomatic alcoholic patients

Sobral-Oliveira¹,

Faintuch²,

Guarita³

et al. 2011

Arq. Gastroenterol.

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-Context -Alcoholism may interfere with nutritional status, but reports are often troubled by uncertainties about ingested diet and organ function, as well as by ongoing abuse and associated conditions. Objective -To identify nutritional and body compartment changes in stable alcoholics without confounding clinical and dietetic variables, a prospective observational pilot study was designed. Three well-matched populations were considered: subjects with chronic alcoholic pancreatitis, alcoholics without visceral disease, and healthy never-drinking adults (controls). Methods -Subjects (n = 60) were asymptomatic males with adequate diet, no superimposed disease or complication, and alcohol-free for at least 6 months. After exclusions, 48 patients were compared. Variables encompassed dietary recall, bioimpedance analysis, biochemical profile and inflammatory markers. Main outcome measures were body fat, lean body mass, serum lipids, C-reactive protein, and selected minerals and vitamins. Results -Both alcoholic populations suffered from reduced lean body mass (P = 0.001), with well-maintained body fat. Magnesium was depleted, and values of vitamin D and B12 correlated with alcohol abuse. LDL and total cholesterol was increased in alcoholics without pancreatitis (P = 0.04), but not in those with visceral damage. C-reactive protein and serum amyloid A correlated with duration of excessive drinking (P = 0.01).Conclusions -Undernutrition (diminished lean body mass, risk of magnesium and vitamin deficiencies) contrasted with dyslipidemia and increased cardiovascular risk. This second danger was masked during chronic pancreatitis but not in alcoholics without visceral disease. Further studies should focus special requirements of this population.

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Section: Bioimpedance Techniquementioning

confidence: 99%

Nutritional profile of asymptomatic alcoholic patients

Sobral-Oliveira¹,

Faintuch²,

Guarita³

et al. 2011

Arq. Gastroenterol.

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“…Por lo tanto el aumento de peso en las gestantes que participaron en este estudio no estaría actuando como una probable variable de confusión al estar evaluando el perfil lipídico, ya que es sabido que la obesidad tiene una influencia directa sobre los mismos (30).…”

Section: Discussionunclassified

Perfil Lipídico Por Trimestre De Gestación en Una Población De Mujeres Adultas

Benítez

Bonneau

Rascón³

et al. 2010

Rev. chil. obstet. ginecol.

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RESUMENAntecedentes: En el embarazo se producen variaciones hormonales muy marcadas y estas se asocian con grandes modificaciones del perfil lipídico. Objetivos: Evaluar el perfil lipídico de mujeres adultas por trimestre de gestación y comparar el perfil lipídico de un grupo control de mujeres no embarazadas con gestantes del primer trimestre, que consultan al servicio de Maternidad del Hospital Público Provincial "Dr. Ramón Madariaga". Método: Se estudiaron 248 embarazadas, 69 en primer trimestre, 78 segundo y 101 tercero. Además un grupo control de 43 no gestantes con distribución etárea, índice de masa corporal y criterios de exclusión similares al grupo de gestantes. Se extrajo sangre con 12 horas de ayuno para las determinaciones bioquímicas, las cuales fueron realizadas por métodos enzimáticos colorimétricos, con controles de calidad interno y externo. Resultados: Se encontró que colesterol total, triglicéridos, col-VLDL, col-LDL, los índices colesterol total/col-HDL y triglicéridos/col-HDL, fueron aumentando significativamente en cada trimestre, mientras que el c-HDL no presentó diferencias. Los valores de percentilo 95 del tercer trimestre para CT de 321 mg/dl y TG 371 mg/dl, podrían ser utilizados como valores de corte en nuestra población. Cuando se comparó mujeres no gestantes versus embarazadas del primer trimestre no se encontraron cambios significativos. Conclusiones: El seguimiento del perfil lipídico de las gestantes podría convertirse en una herramienta diagnóstica que permita monitorear aumentos que superen lo considerado como fisiológico, llevando a un adecuado control prenatal. PALABRAS CLAVE: Riesgo aterogénico, embarazo, perfil lipídico SUMMARY Background:In pregnancy hormonal changes occur very marked and these are associated with major changes in the lipid profile. Aims: To evaluate the lipid profile of adult women during normal pregnancy in the first, second and third trimester and to compare the lipid profile of woman who are not pregnant with the lipid profile of woman who are in the first trimester of gestation and who are attended at the Maternity Public and Provincial Hospital "Dr. Ramón Madariaga". Methods: 248 pregnant women were evaluated of which: 69 women were in the first trimester; 78 women were in the second trimester and 101 women were in the third trimester. In addition a control group of 43 non-pregnant women with age distribution, body mass index and exclusion criteria similar to the group of pregnant women. Blood was extracted after twelve hours fasting to get the biochemical determinations which results were gotten by enzymatic colorimetric methods, with internal and external quality control. Results: It was found that total cholesterol; triglycerides, very low density and low density lipoprotein, the total cholesterol index/ high density lipoprotein y triglycerides/ high

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“…Adipose mass distribution is very important for the assessment of obesity, because complications of obesity are caused mostly by visceral fat accumulation. The size of abdominal fat, especially its visceral depot, is responsible for the occurrence of insulin resistance, metabolic complications and cardiovascular diseases in obese [6]. Measurement of waist circumference is recommended to mark intra-abdominal fat depots and its correlates with cardiometabolic risk factors [6].…”

Section: Influence Of Vitamin D Deficiency On Cardiometabolic Risk Inmentioning

confidence: 99%