Normal references of right ventricular strain values by two-dimensional strain echocardiography according to the age and gender

Abstract

Right ventricular (RV) strain values by 2-dimensional strain echocardiography (STE) can be used as objective markers of RV systolic function. However, there is little data about normal reference RV strain values according to age and gender. We measured normal RV strain values by STE. RV strain values were analyzed from the digitally stored echocardiographic images from NORMAL (Normal echOcardiogRaphic diMensions and functions in KoreAn popuLation) study for the measurement of normal echocardiographic values performed in 23 Korean university hospitals. We enrolled total 1003 healthy persons in the NORMAL study. Of them, we analyzed 2-dimensional RV strain values in 493 subjects (261 females, mean 47 ± 15 years old) only with echocardiographic images by GE machines. Their LV systolic and diastolic functions were normal. RV fractional area change was 48 ± 6% and tricuspid annular plane systolic excursion was 23 ± 3 mm. Total RV global longitudinal peak systolic strain (RVGLS) was -21.5 ± 3.2%. Females had higher absolute RVGLS (-22.3 ± 3.3 vs -20.7 ± 2.9%, p < 0.001) than males. Younger (<50 years old) females had higher absolute RVGLS (-22.9 ± 3.2 vs -20.5 ± 2.8%, p < 0.001) than age matched males. RVGLS in females gradually increased according to age (p for trend = 0.002) and becomes almost similar in age ≥50 years. However, this trend was not seen in males (p for trend = 0.287), and younger males had similar RVGLS value to that of older males (age ≥50 years, -20.5 ± 2.8 vs -20.9 ± 3.1%, p = 0.224). We calculated normal RVGLS values in normal population. Females have higher absolute strain values than males, especially in younger age groups (<50 years old).

Cardiovascular imaging 2018 in the International Journal of Cardiovascular Imaging

“…However, there is little data about normal reference right ventricular strain values according to age and gender. Park et al analysed right ventricular strain data from the digitally stored echocardiographic images from NORMAL (Normal echOcardio-gRaphic diMensions and functions in KoreAn popuLation) study for the measurement of normal echocardiographic values performed in 23 Korean university hospitals [38]. They enrolled in total 1003 healthy persons in the NOR-MAL study.…”

Incremental value of three‐dimensional transthoracic echocardiography over the two‐dimensional modality in the assessment of right heart compression and dysfunction produced by pectus excavatum

“…We also review in tabular form the salient features of this deformity, the current literature dealing with 2D and 3DTTE findings in this deformity and, for comparison purposes, RV, RA, and TVA 2DTTE/3DTTE findings in normal/healthy subjects. The latter include not only available guidelines but also studies published in the literature after the guidelines were formulated (Tables , Figure ) …”

“…End diastole defined as one frame after tricuspid valve closure which corresponded to beginning of QRS complex of EKG in our patient. End systole defined as one frame before TV opening . RV/RA volumes and EF measured using Tomtec software RV EDV and RV ESV defined as maximum RV volume at end diastole (one frame after TV closure) and at respectively .…”

“…End systole defined as one frame before TV opening . RV/RA volumes and EF measured using Tomtec software RV EDV and RV ESV defined as maximum RV volume at end diastole (one frame after TV closure) and at respectively . RA maximum vol is volume measured at largest RA area defined as one frame just before TV opening.…”

“…RA minimum vol is volume measured at smallest RA area one frame after TV closure. PRE‐A vol defined as RA volume measured corresponding to P wave of EKG …”