Normal Reference for Bone Density in Healthy Chinese Children

Xu, Hao; Chen, Jia‐Xuan; Gong, Jian; Tian-min, Zhang; Wu, Qiaobing; Yuan, Zuyi; Wang, Jinping

doi:10.1016/j.jocd.2007.05.005

Cited by 21 publications

(21 citation statements)

References 25 publications

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“…In general, Thai children have lower mean BMDLS (6%) than Caucasian [24]. On the contrary, our mean BMD reference values are 8% and 4% higher than those of Indian (N = 920; BMDLS) and Chinese children (N = 877, BMDTB), respectively [15], [17]. These differences among Asian ethnicity are demonstrated in Figure 4 comparing data between Thai vs. Indian and Chinese children.…”

Section: Discussionmentioning

confidence: 62%

“…However, BMD references of Asian children are limited; only Japanese, Chinese, Korean and Indian data are available and none from Southeast Asian population [14], [15], [16], [17]. Our study is the first study to provide the normative reference data for BMDLS, BMDTB, BMADLS, BMCLS, BMCTB, BALS, BATB and LBM values measured by DXA (Lunar Prodigy) in healthy Thai children and adolescents aged 5–18 years.…”

Section: Discussionmentioning

confidence: 99%

“…Therefore, ethnic-specific normative BMD data using a similar BMD measurement technique should be used for accurate BMD interpretation. There have been previous reports of normative BMD data for children of Caucasian [10], [11], [12], [13] and Asian populations including Japanese, Chinese, Korean and Indian [14], [15], [16], [17]. However, the normative BMD data for Southeast Asian including Thai children and adolescents are not currently available.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

A Normal Reference of Bone Mineral Density (BMD) Measured by Dual Energy X-Ray Absorptiometry in Healthy Thai Children and Adolescents Aged 5–18 Years: A New Reference for Southeast Asian Populations

et al. 2014

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Ethnic-specific normative data of bone mineral density (BMD) is essential for the accurate interpretation of BMD measurement. There have been previous reports of normative BMD data for Caucasian and Asian children including Japanese, Chinese, Korean and Indian. However, the normative BMD data for Southeast Asian including Thai children and adolescents are not currently available. The goals of our study were 1) to establish normative data of BMD, bone mineral content (BMC), bone area (BA) and lean body mass (LBM) for healthy Thai children and adolescents; aged 5–18 years measured by dual energy X-ray absorptiometry (DXA, Lunar Prodigy) and 2) to evaluate the relationships between BMD vs. age, sex, puberty, weight, height, calcium intake and the age of menarche in our population. Gender and age-specific BMD (L2-4; LS and total body; TB), BMADLS (apparent BMD of the lumbar spine), BMC (L2-4 and total body), BA (L2-4 and total body) and LBM were evaluated in 367 children (174 boys and 193 girls). All parameters increased progressively with age. A rapid increase in BMD, BMC and BMADLS was observed at earlier ages in girls. Gender and Tanner stage-specific BMD normative data were also generated. The dynamic changes of BMD values from childhood to early and late puberty of Thai children appeared to be consistent with those of Caucasian and Asian populations. Using a multiple-regression, weight and Tanner stage significantly affected BMDLS, BMDTB and BMADLS in both genders. Only in girls, height was found to have significant influence on BMDTB and BMADLS. The positive correlation between BMD and several demographic parameters, except the calcium intake, was observed. In summary, we established a normal BMD reference for Thai children and adolescents and this will be of useful for clinicians and researchers to appropriately assess BMD in Thais and other Southeast Asian children.

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Section: Discussionmentioning

confidence: 62%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

A Normal Reference of Bone Mineral Density (BMD) Measured by Dual Energy X-Ray Absorptiometry in Healthy Thai Children and Adolescents Aged 5–18 Years: A New Reference for Southeast Asian Populations

et al. 2014

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“…Weiler et al [10] have reported that Asian infants have lower spine bone mass, which is more than a factor of body size and independent of vitamin D status at birth. Recently, there have been the reports from China about the differences among bone densitometry [3,32], estrogen receptor alpha gene polymorphisms [33], lower nutrition status [34], reference curves for BMD in adults [3] and children [32] and fracture rate [2]. Moreover, some discrepancies have been seen between QUS data and results for Chinese children and adults from other populations [25].…”

Section: Discussionmentioning

confidence: 99%

Reduced tibial speed of sound in Chinese infants at birth compared with Caucasian peers: the effects of race, gender, and vitamin D on fetal bone development

et al. 2010

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“…14,15 All subjects had BMD measured by the same validated densitometer to eliminate measurement error. Individual BMD value was expressed as g/cm 2 and Z-score.…”

Section: Data Collection and Determination Of Bone Mineral Densitymentioning

confidence: 99%

The effect of anticonvulsant use on bone mineral density in non-ambulatory children with cerebral palsy

Cheng

2016

Hong Kong Med J

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Normal Reference for Bone Density in Healthy Chinese Children

Cited by 21 publications

References 25 publications

A Normal Reference of Bone Mineral Density (BMD) Measured by Dual Energy X-Ray Absorptiometry in Healthy Thai Children and Adolescents Aged 5–18 Years: A New Reference for Southeast Asian Populations

A Normal Reference of Bone Mineral Density (BMD) Measured by Dual Energy X-Ray Absorptiometry in Healthy Thai Children and Adolescents Aged 5–18 Years: A New Reference for Southeast Asian Populations

Reduced tibial speed of sound in Chinese infants at birth compared with Caucasian peers: the effects of race, gender, and vitamin D on fetal bone development

The effect of anticonvulsant use on bone mineral density in non-ambulatory children with cerebral palsy

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