Nonlinear Interaction of Electromagnetic Radiation at the Cell Membrane Level: Response to Stochastic Fields

Abstract

Abstract-A general rigorous analytic framework for computing the transmembrane potential shift resulting from the nonlinear voltagecurrent membrane relationship in response to wideband stochastic electromagnetic radiation is outlined, based on Volterra functional series. The special case of an insulated cylindrical cell with HodgkinHuxley membrane in an infinite homogeneous medium is worked out in detail, for the simplest case where the applied electric is normal to the cell axis, and independent from the axial coordinate. Representative computational results for a zero-average stationary band-limited white Gaussian incident field are illustrated and briefly discussed.

Electromagnetic and Thermal Analyses of Improved Gtem Cells for Bioelectromagnetic Experiments

“…For this aim, different exposure systems have been proposed for in vitro [1][2][3][4] and in vivo [5][6][7] dosimetric experiments exploiting different electromagnetic devices (e.g., resonant waveguides, Wire Patch Cells (WPC), Transverse Electromagnetic (TEM) cells) and also GHz Transverse Electromagnetic (GTEM) cells [8][9][10]. Further insight in the bioelectromagnetic problem is given by numerical models which analyze the whole body dosimetry [11][12][13], the electromagnetic and thermal effects of the irradiation of specific organs (e.g., the human eye or the brain) [14,15], the electromagnetic interaction at the cell membrane level [16] or the Specific Absorption Rate (SAR) distribution of in vitro cell cultures [17].…”