Non-syndromal, true congenital ankylosis of the temporomandibular joint: a case report

Ajike, SO; Chom, ND; Amanyeiwe, U E; Adebayo, Ezekiel Taiwo; Ononiwu, CN; Anyiam, J O; Ogala, W N

doi:10.1590/s0043-31442006000600015

Cited by 8 publications

(6 citation statements)

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“…Most incidents of TMJ ankylosis occur after a trauma or an infection. Cases of congenital TMJ ankylosis are relatively rare, representing about 3% of TMJ ankylosis incidents (Converse, 1979;Tideman and Doddridge, 1987;Komorowska, 1997;Ajike et al, 2007;Mortazavi and Motamedi, 2007). However, little is known about genetic alterations that cause congenital TMJ ankylosis.…”

Section: Introductionmentioning

confidence: 99%

Shox2-deficiency leads to dysplasia and ankylosis of the temporomandibular joint in mice

Wei

et al. 2008

Mechanisms of Development

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The temporomandibular joint (TMJ) is a unique synovial joint whose development differs from the formation of other synovial joints. Mutations have been associated with the developmental defects of the TMJ only in a few genes. In this study, we report the expression of the homeobox gene Shox2 in the cranial neural crest derived mesenchymal cells of the maxilla-mandibular junction and later in the progenitor cells and undifferentiated chondrocytes of the condyle as well as the glenoid fossa of the developing TMJ. A conditional inactivation of Shox2 in the cranial neural crest-derived cells causes developmental abnormalities in the TMJ, including dysplasia of the condyle and glenoid fossa. The articulating disc forms but fuses with the fibrous layers of the condyle and glenoid fossa, clinically known as TMJ ankylosis. Histological examination indicates a delay in development in the mutant TMJ, accompanied by a significantly reduced rate of cell proliferation. In situ hybridization further demonstrates an altered expression of several key osteogenic genes and a delayed expression of the osteogenic differentiation markers. Shox2 appears to regulate the expression of osteogenic genes and is essential for the development and function of the TMJ. The Shox2 conditional mutant thus provides a unique animal model of TMJ ankylosis.

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Section: Introductionmentioning

confidence: 99%

Shox2-deficiency leads to dysplasia and ankylosis of the temporomandibular joint in mice

Wei

et al. 2008

Mechanisms of Development

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“…Increased airway resistance &corpulmonale may occur 2 . Structural encroachment of oropharyngeal lumen, subatmosphericintrapharyngeal pressure, hypo tonicity of oropharyngeal muscles resulted in airway obstruction.…”

Section: Discussionmentioning

confidence: 99%

“…Facial asymmetry, malocclusion, anemia, malnutrition may are the consequences. It also leads to increased airway obstruction, obstructive sleep apnea and corpulmonale 2 . Airway obstruction is secondary to structural encroachment on or pharyngeal and hypo pharyngeal lumen, subatmosphericintrapharyngeal pressure and hypotonocity of oropharyngeal muscles 3 .…”

Section: Introductionmentioning

confidence: 99%

Anaesthetic Management of Temporomandibular Joint Ankylosis without Fibrotic Bronchoscope- A Review of 31 Cases

2013

IOSR-JDMS

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“…La anquilosis de la ATM es una patología que involucra la fusión del cóndilo mandibular con la base del cráneo (22,23), siendo una de las más serias e incapacitantes patologías de la cavidad oral (2-4). Actualmente no existen datos epidemiológicos poblacionales en la literatura en relación a la anquilosis de la ATM, por lo que es difícil dimensionar el problema a nivel global.…”

Section: Discusión Y Conclusionesunclassified

“…Aunque independiente de cuál sea la estrategia operatoria utilizada se llega al consenso de que un diagnóstico temprano de la patología es sumamente importante en cuanto las probabilidades de éxito del tratamiento, pudiendo de esta manera actuar oportunamente, evitando consecuencias y secuelas mayores (22,23). Del mismo modo, el proceso de re-habilitación postoperatorio ha demostrado ser indispensable si se pretende lograr resultados óptimos y perdurables (22).…”

Section: Discusión Y Conclusionesunclassified

Anquilosis de la articulación temporomandibular: una revisión de la literatura

Molina¹,

Aguayo²,

Ulloa³

et al. 2013

Av Odontoestomatol

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La anquilosis de la articulación temporomandibular (ATM) corresponde a un trastorno temporomandibular clasificado dentro de la hipomovilidad mandibular crónica. La literatura define anquilosis como una inmovilidad anormal de la mandíbula, desorden que lleva a una restricción de la apertura bucal con reducción parcial de los movimientos mandibulares o una completa inmovilidad de la mandíbula. El objetivo del presente artículo es realizar una revisión en cuanto a la clasificación, epidemiología, etiopatogenia, diagnóstico y tratamiento de la anquilosis de la articulación temporomandibular. Palabras clave: Articulación temporomandibular, trastornos temporomandibulares, anquilosis temporomandibular. SUMMARY Ankylosis of the temporomandibular joint (TMJ) corresponds to a temporomandibular disorder classified into chronic mandibular hypomobility. Ankylosis defines literature as an abnormal jaw immobility disorder that leads to a restriction of mouth opening with partial reduction of mandibular movement or complete immobility of the jaw. The aim of this article is to review the classification, epidemiology, etiology, diagnosis and treatment of temporomandibular joint ankylosis.

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Non-syndromal, true congenital ankylosis of the temporomandibular joint: a case report

Cited by 8 publications

References 0 publications

Shox2-deficiency leads to dysplasia and ankylosis of the temporomandibular joint in mice

Shox2-deficiency leads to dysplasia and ankylosis of the temporomandibular joint in mice

Anaesthetic Management of Temporomandibular Joint Ankylosis without Fibrotic Bronchoscope- A Review of 31 Cases

Anquilosis de la articulación temporomandibular: una revisión de la literatura

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