Non Allergic Rhinitis: Prevalence, Clinical Profile and Knowledge Gaps inLiterature

Bhargava, Deepa; Bhargava, Kamlesh; Al-Abri, Ahmed; Al-Bassam, Wameedh; Al‐Abri, Rashid

doi:10.5001/omj.2011.106

Cited by 15 publications

(14 citation statements)

References 17 publications

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“…19,20 In our study, the prevalence for specialist tertiary care setting was found to be 7%, which compared to the prevalence of NAR given in the literature is lower. 4 We found the prevalence of perennial AR was much higher (84%) compared to seasonal AR (16%). One reason could be the geographical and topographical features leading to lack of vegetation and pollen in Oman's desert terrain, the same factors explain the low prevalence of seasonal AR.…”

Section: Discussionmentioning

confidence: 85%

Allergic Rhinitis and Associated Comorbidities: Prevalence in Oman with Knowledge Gaps in Literature

Al-Abri¹,

Bharghava²,

Kurien³

et al. 2014

Oman Med J

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The prevalence of AR in the adult population presenting with nasal symptoms was found to be 7%, with associated chronic rhinosinusitis present in a third of these patients. However, there appears to be substantial knowledge gaps regarding the association of other comorbidities, like otitis media, bronchitis and bronchial asthma, the long-term outcomes of medical management, and indication of surgical intervention in patients with AR. Future research in AR among Omani patients should aim to address these issues.

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Section: Discussionmentioning

confidence: 85%

Allergic Rhinitis and Associated Comorbidities: Prevalence in Oman with Knowledge Gaps in Literature

Al-Abri¹,

Bharghava²,

Kurien³

et al. 2014

Oman Med J

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“…In chronic or recurrent paranasal sinus disease, MSCT is used both as a diagnostic tool to identify anatomical anomalies and mucosal pathology and as a preoperative map to guide the surgeon prior to endoscopic sinus surgery. Ostiomeatal complex is the key area in the pathogenesis of chronic or recurrent sinusitis; many anatomic variations may affect this region and may play an important role in the obstruction of the ostiomeatal complex [ 5 ]. One of the prerequisites for successful FESS is knowledge of the complex anatomy of paranasal sinuses.…”

Section: Discussionmentioning

confidence: 99%

“…The reported frequency of anatomic variations in patients with chronic rhinosinusitis is as follows: agger nasi cells in 15%, Haller cells in 7%, conchae bullosa in 30%, paradoxical middle turbinate in 24%, and septal deviation in 21% of patients [ 5 ]. Outcomes of FESS for chronic rhinosinusitis depend on an accurate evaluation of the disease and paranasal anatomic variations.…”

Section: Introductionmentioning

confidence: 99%

Diagnostic Performance of Multidetector Computed Tomography (MDCT) in Diagnosis of Sinus Variations

Alsowey¹,

Abdulmonaem²,

Elsammak³

et al. 2018

Pol J Radiol

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SummaryBackgroundIn this prospective study, we looked for correlations between anatomic variants of paranasal sinuses and chronic or recurrent sinusitis.Material/MethodsTwo hundred and forty (240) patients with clinical features of chronic rhinosinusitis were examined; patients with first-onset or allergic sinusitis and pregnant females were excluded. Routine multi-slice CT of the paranasal sinuses was performed to look for mucosal disease of the paranasal sinuses, drainage pathways, and presence of anatomical variations and their relation to known sinus drainage pathways.ResultsAnatomic variations were very frequent, and we classified them into four easily recognized groups: nasal septum variations, middle turbinate variations, uncinate process variations, and ethmoidal variations. Deviated nasal septum was the most frequent variation in patients with chronic or recurrent sinusitis, and it was detected in 48.8% of cases. Agger nasi cells and concha bullosa were equally frequent (30.6%), and Haller cells were detected in 11.2%. Uncinate process variations were detected in 18.1%, and the large ethmoid bulla was detected in 10%.ConclusionsThe importance of anatomic variations is that they can compromise drainage pathway of the related sinus, which results in inflammatory sinus disease. Anatomical variations are not diseases on their own and may be present as incidental findings in patient with chronic sinusitis.

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“…However, the lack of universal terminology of NAR and, in particular its phenotype using objective criteria, remain the most striking gaps in our knowledge at present (16) .…”

Section: Introductionmentioning

confidence: 99%

Role of inflammation in non-allergic rhinitis

Corso¹,

Battista²,

Pandolfini³

et al. 2014

Rhin

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Objective: To investigate the role of inflammation in non-allergic rhinitis (NAR) patients in a large series to establish the prevalence of different NAR-subtypes, clinical features and the role of nasal cytology in the diagnostic algorithm. Methodology:Patients were selected out of 3650 individuals who spontaneously presented at our institution. We consecutively enrolled 519 NAR-patients in an analytical cross-sectional study between November 2007 and June 2013 (level of evidence: 3b).All patients underwent rhinological evaluation including symptoms questionnaire, endoscopy, CT scan, allergy tests and nasal cytology. Results:The inflammatory cell infiltrate affects the severity of symptoms differently, allowing for identification of different phenotypes of NAR. We distinguished two groups: "NAR without inflammation"(NAR-) and "NAR with inflammation"(NAR+), in addition to different NAR-subtypes with inflammation. A significant difference was observed in terms of clinical symptoms and association with comorbidities (previously diagnosed asthma and aspirin intolerance) between NAR-, NAR+ and between different NAR+ subtypes. Conclusion:Our data suggest that NAR-and NAR with neutrophils behave similarly, showing lower symptom score values and a lower risk of association with comorbidities compared to NAR with eosinophils and mast cells (singularly or mixed). In our belief it is very important to establish the presence and type of inflammation in non-allergic rhinitis patients and nasal cytology is a very useful test in correct differential diagnosis.

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Non Allergic Rhinitis: Prevalence, Clinical Profile and Knowledge Gaps inLiterature

Cited by 15 publications

References 17 publications

Allergic Rhinitis and Associated Comorbidities: Prevalence in Oman with Knowledge Gaps in Literature

Allergic Rhinitis and Associated Comorbidities: Prevalence in Oman with Knowledge Gaps in Literature

Diagnostic Performance of Multidetector Computed Tomography (MDCT) in Diagnosis of Sinus Variations

Role of inflammation in non-allergic rhinitis

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