Nickel‐Catalyzed Synthesis of N‐(Hetero)aryl Carbamates from Cyanate Salts and Phenols Activated with Cyanuric Chloride

Abstract

A simple and efficient domino reaction has been designed and employed for the one‐pot synthesis of N‐(hetero)aryl carbamates through the reaction between alcohols and in‐situ produced (hetero)aryl isocyanates in the presence of a nickel catalyst. The phenolic C−O bond was activated via the reaction of phenol with cyanuric chloride (2,4,6‐trichloro‐1,3,5‐triazine (TCT)) as an inexpensive and readily available reagent. This strategy provides practical access to N‐(hetero)aryl carbamates in good yields with high functional groups compatibility.

A Compendium of the Most Promising Synthesized Organic Compounds against Several Fusarium oxysporum Species: Synthesis, Antifungal Activity, and Perspectives

“…Inaloo et al (2020) have reported a methodology for the synthesis of N -(hetero)aryl carbamates that use a domino reaction in a single vessel from alcohols and (hetero)aryl isocyanates produced in situ in the presence of a catalyst of nickel [ 49 ]. The phenolic C-O bond is activated in this protocol by phenol’s reaction with cyanuric chloride (2,4,6-trichloro-1,3,5-triazine, TCT).…”

Fe3O4@glutamate MOF functionalized with Co nanoparticles anchored dicyandiamde: As a capable heterogeneous and reusable nanocatalyst in C–P cross‐coupling reaction

“…Although this coupling reaction has been widely used in both academies and industries, nevertheless, it suffers from some drawbacks such as longer reaction times, high reaction temperatures, strong bases, hazardous solvents, high‐cost transition metal catalysts, and being environmentally unfavorable. [ 11–14 ] In recent years, a vast number of the transition metal catalysts, including palladium, [ 15 ] nickel, [ 16,17 ] platinum, [ 18 ] rhodium, [ 19 ] and copper [ 20,21 ] catalysts, have been implemented for the direct phosphorylation reaction. However, most of these catalyzed protocols with transition metals have polluted the environment and its compartments.…”

Green Synthesis of New Category of Pyrano[3,2-c]Chromene-Diones Catalyzed by Nanocomposite as Fe3O4@SiO2-Propyl Covalented Dapsone-Copper Complex

“…Magnetic nanoparticles (MNPs) as catalysts are interesting materials because of their high surface area, unique magnetic properties, and high catalytic activity. They were used as magnetic fluids catalysis and magnetic resonance imaging (MRI) data storage and environmental remediation (Rezaee Nezhad et al, 2014;Mokhtary, 2016;Rezayati et al, 2016;Fekri and Maleki, 2017;Abbasi et al, 2017;Sardarian et al, 2019;Inaloo et al, 2020a;2020b;2020c;2020d).…”