New Unstable Bladder Model in Hypercholesterolemia Rats

Son, Hwancheol; Lee, Sang Lin; Park, ﻿Won Hee; Park, Kwanjin; Park, Sohyun; Kang, Myung‐Hee; Kim, Dae-Yong; Kim, Soo Woong; Paick, Jae‐Seung

doi:10.1016/j.urology.2006.09.062

Cited by 26 publications

(32 citation statements)

References 29 publications

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“…The effect of hypercholesterolemia on detrusor contractility has been investigated in a limited number of studies (12)(13)(14)(15)(16). It has been shown that a number of neurotransmitters released in response to neural stimulation, which is mainly mediated by the cholinergic system and in addition by the purinergic system (17), are likely to be altered under pathological conditions (14,18,19).…”

Section: Introductionmentioning

confidence: 99%

“…It has been shown that a number of neurotransmitters released in response to neural stimulation, which is mainly mediated by the cholinergic system and in addition by the purinergic system (17), are likely to be altered under pathological conditions (14,18,19). Since urinary bladder dysfunctions are increasing in incidence, especially in the elderly population where hypercholesterolemia is also common (20,21), we aimed to investigate the in vitro contractions of detrusor smooth muscle strips stimulated by an electrical field and the cholinergic and noncholinergic neurotransmission in hypercholesterolemic rats.…”

Section: Introductionmentioning

confidence: 99%

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The effect of hypercholesterolemia on the contractions of detrusor strips in response to neural stimulation in rats

Karaismailoğlu¹,

Balkanci²,

Pehlivanoğlu³

et al. 2013

Turk J Med Sci

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Currently the most widely used machine for precision seeding of cotton and maize seed is vacuum type. Th e capture of seeds by vacuum plate and the release of seeds from the vacuum plate should be performed precisely without missing or doubling. Th e physical phenomena should be clarifi ed theoretically to understand how the precision seeding mechanism works. To solve these problems, an attempt was made to develop a nomogram using equations describing the technical characteristics of the seeder used in this study and to describe the seed capture mechanism relying on basic principles of fl uid mechanics and aerodynamic properties of seeds. Seed spacing accuracy tests were performed to test the theory on a sticky belt in the laboratory. Quality of feed index, miss and multiple indices, and precision have been taken as a set of criteria for seed spacing accuracy. Th e regression models developed using the data obtained via sticky band tests showed that 16 seeds s -1 was the upper limit of seed release frequency (SRF) for cotton and maize seeds. Th e upper limit of vacuum plate peripheral speed was found to be 0.34 m s -1 . Th e use of 72 holes instead of 26 holes in the vacuum plate at 6.3 kPa created a vacuum band in the width of 10 mm around holes and this increased the multiple index and caused a reduction in seeding performance. For this reason, the use of vacuum plates with 60 or 52 holes is recommended for cotton seed. Th e forward speed of either 1.0 or 1.5 m s -1 was found to be acceptable for the seed spacing of 0.05 and 0.10 m, respectively. Aerodynamic calculations verifi ed that widely used vacuum plates with 26 holes were the appropriate ones for seeding maize seeds. Th e performance indices, namely the quality of feed, and miss and multiple indices, reduced signifi cantly for cotton and maize seeding when the precision metering unit was run at 20% (11°) slope to the right as compared to the no slope condition.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

The effect of hypercholesterolemia on the contractions of detrusor strips in response to neural stimulation in rats

Karaismailoğlu¹,

Balkanci²,

Pehlivanoğlu³

et al. 2013

Turk J Med Sci

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“…A ocorrência de hipercolesterolemia induzida por dieta em modelo experimental (Sérougne et al, 1995;Asahina et al, 2005;Guerra et al, 2007;Zulet et al, 2007) relaciona-se com aumento prostático, hiperatividade detrusora e disfunção erétil (Son et al, 2007;Rahman et al, 2007;Xie et al, 2007). Além disso, sugere-se que a aterosclerose induzida por hipercolesterolemia ocasionaria um quadro de isquemia crônica vesical, acelerando a remodelação vesical que ocorre após OIV, resultando em maior prejuízo à sua função.…”

Section: Hipercolesterolemiaunclassified

“…Perfil semelhante foi observado nos estudos conduzidos por Sérougne et al (1995), Guerra et al (2007), Son et al (2007) e Zulet et al (2007.…”

Section: Colesterol Totalunclassified

“…Rahman et al (2007) observaram espessamento da parede vesical e aumento dos receptores purinérgicos nos ratos hipercolesterolêmicos. Já o estudo conduzido por Son et al (2007) não identificou qualquer alteração morfológica vesical por meio das colorações HE e tricrômio de Masson. No entanto, estas não são colorações específicas para detecção de colágeno (Rich, Whittaker, 2005).…”

Section: Colesterol Totalunclassified

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Influência da dieta hipercolesterolêmica na remodelação do colágeno da matriz extracelular da parede vesical em ratos

Nunes¹

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Nunes, pelos quais tenho enorme orgulho e gratidão. Ela, pela sua força, coragem e apoio. Ele, pela generosidade, sabedoria e incansável dedicação.À minha irmã, Maria Carolina Vita Nunes, pelos seus conselhos e incentivo.À minha avó, Elza Nascimento Vita, pelo carinho e atenção. À minha esposa, Nathalia Perazzo Tereran, grande amor da minha vida, que em todos os momentos retribuiu esse amor com incessante dedicação e cumplicidade, e que me deu a maior alegria da minha vida, meu filho Diego Perazzo Vita Nunes, hoje minha maior fonte de inspiração e força.

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The effects of chronic hyperlipidemia on bladder function in myocardial infarction‐prone Watanabe heritable hyperlipidemic (WHHLMI) rabbits

Yoshida¹,

Masunaga

Nagata

et al. 2010

Neurourology and Urodynamics

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New Unstable Bladder Model in Hypercholesterolemia Rats

Cited by 26 publications

References 29 publications

The effect of hypercholesterolemia on the contractions of detrusor strips in response to neural stimulation in rats

The effect of hypercholesterolemia on the contractions of detrusor strips in response to neural stimulation in rats

Influência da dieta hipercolesterolêmica na remodelação do colágeno da matriz extracelular da parede vesical em ratos

The effects of chronic hyperlipidemia on bladder function in myocardial infarction‐prone Watanabe heritable hyperlipidemic (WHHLMI) rabbits

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