New Treatment for Pitted Scars

Treatment of Depressed Scars with Fibrin Foam—Seventeen Years of Experience

“…In our biopsies of areas injected with fibrin foam, we noted early invasion by white blood cells, then phagocytosis, and finally, replacement by fibroblasts, fibrocytes, and normal collagen. In a specimen examined three months after injection, no foreign body or inflammatory reaction could be found. Bailey and Ingraham, who used fibrin foam to promote blood coagulation in neurosurgical operations, found similar complete disappearance of fibrin foam after two months.…”

“…Ross, in studying the repair of normal wounds, found the following sequence of events: formation of fibrin; immigration of polymorphonuclear leukocytes, lymphocytes, and macrophages; infiltration by fibroblasts, and finally, the formation of normal fibrous tissue. In our biopsies of areas injected with fibrin foam, we noted early invasion by white blood cells, then phagocytosis, and finally, replacement by fibroblasts, fibrocytes, and normal collagen. In a specimen examined three months after injection, no foreign body or inflammatory reaction could be found.…”

“…The technique, as previously described, is as follows: the scar is outlined with a skin‐marking pencil. Novocain is injected beneath the scar with a 26 gauge needle, and that needle hole is then enlarged by injecting a small amount of novocain through a 20 gauge needle.…”

Postacne Scarring: A Review of its Pathophysiology and Treatment

“…Undermining scars is not new and for many years has been used as an adjunct to Fibrin foam 69 or Fibrel implantation, [70][71][72] dermal grafting, [73][74][75] and microlipoinjection. As a stand-alone corrective technique it has only recently been described 76,77 as subcision or dermal scarification.…”

Silicone, Fibrel, and Collagen Implantation for Facial Lines and Wrinkles

“…Fibrel evolved from work performed some decades ago by Dr. Arthur Spangler, a Boston dermatologist 13,14 . Spangler reported on the use of “Fibrin Foam” for treatment of depressed scars.…”