Treatment of Depressed Scars with Fibrin Foam—Seventeen Years of Experience

Abstract

Over 7,000 depressed scars in 527 patients were treated by the fibrin foam method. This paper discusses the method and material on this treatment.

The History of Substances for Soft Tissue Augmentation

“…In 1957 Spangler reported the efficacy of “fibrin foam” in treating depressed scars in 23 patients. Subsequently, he reported good to excellent results in treating 7000 patients with this substance 52 . The composition and fabrication of Fibrel, the modern descendant of fibrin foam, was further delineated by Gottlieb 53 .…”

The History of Substances for Soft Tissue Augmentation

“…52 The composition and fabrication of Fibrel, the modern descendant of fibrin foam, was further delineated by Gottlieb. In 1957 Spangler reported the efficacy of "fibrin foam" in treating depressed scars in 23 patients.…”

Silicone, Fibrel, and Collagen Implantation for Facial Lines and Wrinkles

“…Fibrel evolved from work performed some decades ago by Dr. Arthur Spangler, a Boston dermatologist 13,14 . Spangler reported on the use of “Fibrin Foam” for treatment of depressed scars.…”