The History of Substances for Soft Tissue Augmentation

Klein, Arnold William; Elson, Melvin L.

doi:10.1046/j.1524-4725.2000.t01-1-00512.x

Cited by 23 publications

(21 citation statements)

References 43 publications

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“…Synthetic fillers include non-animal hyaluronic acid, polymethyl methacrylate (PMMA) microspheres, and hydroxylapatite micro-particles, among others. Several authors have also described similar categories (Jansen and Graivier 2003, 2006; Rohrich et al 2003; Tzikas 2004; Murray et al 2005; Narins and Bowman 2005; Broder and Cohen 2006; Klein and Elson 2006; Sengelmann et al 2007).…”

Section: Classification and Ideal Properties Of Facial Fillersmentioning

confidence: 90%

Use of calcium hydroxylapatite (Radiesse<sup>®</sup>) for facial augmentation

Jacovella

2008

CIA

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Section: Classification and Ideal Properties Of Facial Fillersmentioning

confidence: 90%

Use of calcium hydroxylapatite (Radiesse<sup>®</sup>) for facial augmentation

Jacovella

2008

CIA

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“…Autologous fat grafting has become popular for soft tissue augmentation throughout the entire body (22, 23). There is, however, much variability in the literature regarding the high resorption of fat grafts (24).…”

Section: Stem Cellsmentioning

confidence: 99%

The Role of Stem Cells in Aesthetic Surgery

McArdle

Senarath-Yapa

Walmsley

et al. 2014

Plastic and Reconstructive Surgery

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Stem cells are attractive candidates for the development of novel therapies, targeting indications that involve functional restoration of defective tissue. Although most stem cell therapies are new and highly experimental, there are clinics around the world that exploit vulnerable patients with the hope of offering supposed stem cell therapies, many of which operate without credible scientific merit, oversight, or other patient protection. We review the potential, as well as drawbacks, for incorporation of stem cells in cosmetic procedures. A review of FDA-approved indications and ongoing clinical trials with adipose stem cells is provided. Furthermore, a “snapshot” analysis of websites using the search terms “stem cell therapy” or “stem cell treatment” or “stem cell facelift” was performed. Despite the protective net cast by regulatory agencies such as the FDA and professional societies such as the American Society of Plastic Surgeons, we are witnessing worrying advertisements for procedures such as stem cell facelifts, stem cell breast augmentations, and even stem cell vaginal rejuvenation. The marketing and promotion of stem cell procedures in aesthetic surgery is not adequately supported by clinical evidence in the majority of cases. Stem cells offer tremendous potential, but the marketplace is saturated with unsubstantiated and sometimes fraudulent claims that may place patients at risk. With plastic surgeons at the forefront of stem cell-based regenerative medicine, it is critically important that we provide an example of a rigorous approach to research, data collection, and advertising of stem cell therapies.

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“…Treatment with dermal fillers is a type of soft-tissue augmentation 1-3 that comprises 2 clinical categories, depending on the type of application: (1) operative (invasive) applications of filling substances or small implants, commonly performed by plastic or craniofacial surgeons, and (2) injectable preparations administered by dermatologists. [4][5][6][7][8][9] The latter category is the subject of the present study.…”

Section: Researchmentioning

confidence: 99%