New Hopane Triterpenes and Antioxidant Constituents from Potentilla Fulgens

Abstract

Phytochemical investigation of the aerial parts of Potentilla fulgens L. led to the isolation of two new triterpenes, potentene A (1) and potentene B (2). In addition, three known compounds afzelchin−4α→8΄΄−catechin (3), epiafzelchin (4) and rutin (5) were isolated. The structures of all these compounds were elucidated by extensive spectroscopic and chemical evidence. Compounds 3, 4, and 5 exhibited significant 1,1,diphenyl-2-picrylhydrazyl radical scavenging activity, with IC 50 values of 1.21, 2.88 and 5.20 mg/mL, respectively; the known standard antioxidant, vitamin C, had a value of 0.44 mg/mL.

Phytochemical Profiles, Antioxidant and Antimicrobial with Antibiofilm Activities of Wild Growing Potentilla visianii Extracts

“…Different biological effects that show some Potentilla species can be explained by the large amount of condensed tannins and flavonoids, which are present in all parts of these plants [21]. For example, compounds from Potentilla fulgens exhibited significant anti-oxidative activity, which is in accordance to our study [22]. Extracts of Potentilla fruticosa possess a relatively large amount of phenolic acids and flavonoids and also show a high degree of antioxidative activity [3,[5][6][7].Literature review of antimicrobial activity of Potentilla species gives different conclusions.…”

Potentilla fulgens: A Systematic Review on Traditional Uses, Pharmacology and Phytochemical Study with Reference to Anticancer Activity

“…Pharmacological studies report that Potentilla fulgens possesses antioxidant (in vitro models), antitumor, hypoglycaemic and antihyperglycemic activities [13][14][15], antioxidant, anti-inflammatory, antiulcerogenic properties.…”

“…Potentilla fulgens is rich in polyphenolic and triterpene constituents [23][24][25][26]. From the root parts of P. fulgens phytochemical investigation led to the isolation of a novel bioflavonoid potifulgene (Epiafzelchin-6-o-8´´ epiafzelchin) along with epicatechin [25]. Two new ursane type triterpenoids, Fulgic acid A [27] and Fulgic acid B were identified and characterized [28].…”

Potentilla and Rubus medicinal plants

“…8 00 -catechin, epiafzelechin, and rutin of P. fulgens exhibited significant 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activity (Jaitak et al, 2010). 8 00 -catechin, epiafzelechin, and rutin of P. fulgens exhibited significant 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activity (Jaitak et al, 2010).…”