Neurofibromatosis type I and anti-phospholipid antibody syndrome: Report of one case

Abstract

Neurofibromatosis type I (NF1) has been only rarely reported in association with anti-phospholipid syndrome (APS

Portal vein thrombosis as a rare cause of abdominal pain: When to consider?

“…Involvement of the skin, bone, soft tissue, arterial system and nervous system is accompanied by multiple sclerosis and malignancy development in various organs and tissues of the body. Association with APS that causes thrombotic disorders has also been reported (8).…”

Antiphospholipid syndrome and neurofibromatosis type I: a coincidence or new association?

“…An association of NF1 and APS, a prothrombotic autoimmune disease, is unusually rare. Very few documented cases fulfill the accepted criteria for a diagnosis of APS (Table 1) (4)(5)(6) . The currently accepted criteria for defining APS are the presence of at least one clinical criterion: ≥1 thromboembolic episodes and/or pregnancy morbidity or spontaneous fetal loss and at least one laboratory criterion: presence of lupus anticoagulant (LA), anticardiolipin antibody or anti-β 2 -glycoprotein 1 (IgG and IgM) on two occasions separated by 12 weeks.…”