Analysis of North environmental factors and they influence on human body have special problem according to absent of statistic stability of any samples parameters. Now it is known as Eskov-Zinchenko effect and the effect needs new theory and new methods for description of specific behavior of biosystems. So we presented the Eskov-Zinchenko effect and new methods of system synthesis. The last method is based on investigation of order parameters and calculation of a special model for cardiointervals aging dynamic and its descriptions.