Network Analysis of Saccharomyces Cerevisiae Colony: Relation between Spatial Position and Generation

Abstract

Yeast colony growth which can grow and produce buds can be modelled by using circular granular cells in two-dimensional form. The organizations of particles in granular materials as modelled as yeast colony growth have complex organizations on a spatial scale. Such organizations may affect how materials respond or reconfigure when exposed to external interference or loading. Particles have been studied in theoretical and require the development and application of appropriate mathematical, statistical, physical and computational frameworks. Usually, granular materials have been explored using particles or circuit models that are implicit. Today the development of network science has emerged as a powerful approach to investigate and characterize heterogeneous architecture in complex systems and diverse methods have yielded interesting insights into granular materials. In this study will learn granular materials (yeast colony growth) with the network-based approach and explore the potential of these frames to provide a useful description of yeast colony growth. This study will focus on finding the relation between the spatial position of the cells and generation that is formed.

Quantifying the Biophysical Impact of Budding Cell Division on the Spatial Organization of Growing Yeast Colonies

“…In each of these previous studies, results focused on the colony as a whole-size, shape and expansion-and not how the colony itself was organized. An additional set of studies used ABMs to investigate the impact of individual cell growth and reproduction times on colony expanse as well as study the relationship between cell generation and birth location in the colony [43][44][45][46][47]. However, likely for computational simplicity, these prior studies focused primarily on populations of a few hundred or few thousand cells.…”