“…It is believed that the effect of maternal estrogens on the vaginal epithelium may predispose newborn female infants to infection. 1 Successful treatment has been reported with metronidazole. 8,9 We speculate that the development of a ''bubbly'' radiographic appearance of this patient's lungs, together with persistent oxygen requirement after several weeks of life following a relatively benign acute phase of her illness, is reminiscent of the condition described by Wilson and Mikity 10 in 1960, and later discussed by Hodgman et al 11 This late-developing syndrome, characterized by cyanosis, retractions, and tachypnea in small premature infants, was reported to have its onset after several weeks of life in infants without respiratory distress at birth.…”