Neonatal<i>Trichomonas vaginalis</i>infection: a case report and review of literature

Trintis, J; Epie, N; Boss, Renee D.; Riedel, Stefan

doi:10.1258/ijsa.2010.010174

Cited by 28 publications

(13 citation statements)

References 13 publications

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“…Vertical transmission is a phenomenon observed in many parasite and host species. Vertical transmission occurs by the transfer of the parasite from mother to offspring during pregnancy ( Toxoplasma gondii ), child birth ( Trichomonas vaginalis ) or lactation ( Toxocara canis ) [ 1 – 4 ]. Congenital infections may cause complications during pregnancy, miscarriages or foetal infections [ 5 , 6 ].…”

Section: Introductionmentioning

confidence: 99%

Vertical Transmission of Babesia microti in BALB/c Mice: Preliminary Report

et al. 2015

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Babesia spp. (Apicomplexa, Piroplasmida) are obligate parasites of many species of mammals, causing a malaria-like infection- babesiosis. Three routes of Babesia infection have been recognized to date. The main route is by a tick bite, the second is via blood transfusion. The third, vertical route of infection is poorly recognized and understood. Our study focused on vertical transmission of B. microti in a well-established mouse model. We assessed the success of this route of infection in BALB/c mice with acute and chronic infections of B. microti. In experimental groups, females were mated on the 1st day of Babesia infection (Group G0); on the 28th day post infection (dpi) in the post- acute phase of the parasite infection (G28); and on the 90th and 150th dpi (G90 and G150 group, respectively), in the chronic phase of the parasite infection. Pups were obtained from 58% of females mated in the post-acute phase (G28) and from 33% of females in groups G90 and G150. Mice mated in the pre-acute phase of infection (G0) did not deliver pups. Congenital B. microti infections were detected by PCR amplification of Babesia 18S rDNA in almost all pups (96%) from the experimental groups G28, G90 and G150. Parasitaemia in the F1 generation was low and varied between 0.01–0.001%. Vertical transmission of B. microti was demonstrated for the first time in BALB/c mice.

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Section: Introductionmentioning

confidence: 99%

Vertical Transmission of Babesia microti in BALB/c Mice: Preliminary Report

et al. 2015

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“…Genital or anal CT infection is nearly always diagnostic of sexual abuse, and even in a child younger than 3 years it should be reported to CPS and an investigation should be completed. TV infection also can be prenatally acquired; the length of infection persistence is unknown (Trintis, Epie, Boss, & Riedel, 2010). Genital TV infection is also diagnostic of sexual abuse and even in a child younger than 3 years should be reported to CPS.…”

Section: Interpretation Of Sti Resultsmentioning

confidence: 99%

Sexually Transmitted Infections and Children: What the PNP Should Know

Hornor¹

2017

Journal of Pediatric Health Care

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Sexual abuse is a problem of epidemic proportions in the United States. In their practice, pediatric nurse practitioners will likely encounter children who have experienced sexual abuse-both those who have and have not previously been identified as victims. Sexually transmitted infections (STIs) are rare in sexually abused children and adolescents. However, when present, they can be crucial to making the diagnosis of sexual abuse and protecting children. This continuing education article will assist the pediatric nurse practitioner in interpreting the relationship between STIs and sexual abuse, correctly testing for STIs, and treating STIs in children and adolescents.

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“…11,18–22 Interestingly, recent research linking trichomonas infections to prostate cancer in men has been accumulating and may add reasons to be more actively screen men for trichomonas. 23–24 The availability of serological detection of circulating antibody to trichomonas may be an additional epidemiological tool for diagnosis of chronic infections, when only very limited amount of pathogens are released in urine or in vaginal secretions.…”

Section: Discussionmentioning

confidence: 99%

Clinical performance of the Solana® Point-of-Care Trichomonas Assay from clinician-collected vaginal swabs and urine specimens from symptomatic and asymptomatic women

Gaydos

Schwebke

Dombrowski

et al. 2017

Expert Review of Molecular Diagnostics

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Background-Solana® (Quidel) is a new rapid (<40 min.) point-of-care (POC) test for qualitative detection of Trichomonas vaginalis (TV) DNA. The assay has two steps: 1) specimen preparation, and 2) amplification and detection using isothermal Helicase-Dependent Amplification (HDA). The objective was to demonstrate the performance of Solana for vaginal swabs and female urines based on comparison to wet mount and TV culture. Performance was also compared to the Aptima-TV assay.Methods-Urine and four clinician-collected vaginal swabs were collected. The first two were used for FDA composite reference (wet mount; InPouch TV Culture). The third swab was used for Solana. Sensitivity/specificity were based on the reference method. A specimen was considered positive if either test was positive. The fourth swab was for Aptima-TV.Results-Vaginal swabs and urines were obtained from 501 asymptomatic and 543 symptomatic women. Prevalence of TV by was 11.5%. For swabs, Solana® demonstrated high sensitivity and specificity from asymptomatic (100%/98.9%) and symptomatic (98.6%/98.5%) women, as well as for urines from asymptomatic (98.0%/98.4%) and symptomatic (92.9%/97.9%) women, compared to the reference method. Compared to Aptima-TV, the sensitivity/specificity was 89.7%/99.0% for swabs and 100%/98.9% for urines. Conclusions-TheSolana® assay performed well compared to the reference assays.

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NeonatalTrichomonas vaginalisinfection: a case report and review of literature

Cited by 28 publications

References 13 publications

Vertical Transmission of Babesia microti in BALB/c Mice: Preliminary Report

Vertical Transmission of Babesia microti in BALB/c Mice: Preliminary Report

Sexually Transmitted Infections and Children: What the PNP Should Know

Clinical performance of the Solana® Point-of-Care Trichomonas Assay from clinician-collected vaginal swabs and urine specimens from symptomatic and asymptomatic women

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