Neonatal septicaemia.

Vesikari, Timo; Janas, M; Gronroos, P; N, Tuppurainen; Renlund, Martin; Kero, Pentti; Koivisto, Maila; Kunnas, M; Heinonen, Kirsti; Nyman, R

doi:10.1136/adc.60.6.542

Cited by 107 publications

(61 citation statements)

References 12 publications

(1 reference statement)

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“…The reported incidence of neonatal septicaemia in developed countries such as Europe and North America ranged between 0.95/1000 live births and 3/1000 live birth [25,26]. This is similar to the reported incidence of 3/1000 live births report by Ayman et al [27] from the United Arab Emirates (UAE).…”

Section: Epidemiology Of Neonatal Septicaemiasupporting

confidence: 77%

“…These results are higher than figures from North America, Europe and the Middle East. This may be explained by the fact that the developed countries have well equipped Hospitals with strong supportive laboratory, the mothers are well informed and know when and where to take their sick new-borns early enough to seek for care [26,27]. Although, these results were lower than the earlier report from Ibadan [22].…”

Section: Epidemiology Of Neonatal Septicaemiacontrasting

confidence: 56%

“…The common risk factors for NNS in the developed world include prematurity and peripartum colonization of the birth canal by GBS [3,26]. In most of the studies from Nigeria, common risk factors included lack of good obstetric care, poor nursery practices, low socio economic status, poor housing conditions, poor personal hygiene, delivery at home/unhygienic environment, prematurity and complications of labour [3,22,29].…”

Section: Risk Factors For Neonatal Septicaemiamentioning

confidence: 99%

“…Group B β-haemolytic streptococci (GBS) and Escherichia coli are important causes of neonatal septicaemia between 2003-2005 in North America [40] and Europe [3,26]. However, in the tropics and subtropics, Gram-negative organisms are the predominant aetiologic agents, especially in the first week of life [3,41].…”

Section: Epidemiology Of Neonatal Septicaemiamentioning

confidence: 99%

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Neonatal Septicaemia in Poor Resource Settings

Pius¹,

Bello²

2017

Pediatric Infect Dis

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Section: Epidemiology Of Neonatal Septicaemiasupporting

confidence: 77%

Section: Epidemiology Of Neonatal Septicaemiacontrasting

confidence: 56%

Section: Risk Factors For Neonatal Septicaemiamentioning

confidence: 99%

Section: Epidemiology Of Neonatal Septicaemiamentioning

confidence: 99%

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Neonatal Septicaemia in Poor Resource Settings

Pius¹,

Bello²

2017

Pediatric Infect Dis

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“…Apesar dos avanços na terapia antimicrobiana, nas medidas de suporte vital e na melhoria dos meios para diagnóstico dos fatores de risco perinatal para infecção, a sepse neonatal é uma das principais causas de morbidade e mortalidade, sendo a sua taxa de mortalidade de aproximadamente 25% [1][2][3] . Sepse neonatal precoce ocorre, geralmente, em até 5 dias de vida, mas o consenso é sua manifestação durante os primeiros sete dias de vida 4 .…”

Section: Introductionunclassified

The influence of intrapartum antibiotic therapy on the diagnosis of early-onset neonatal sepsis

Vieira¹,

Procianoy²,

Mulle³

et al. 1997

J Pediatr (Rio J)

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ResumoObjetivo: Determinar a repercussão do uso de antibióticos pelas mães no resultado das hemoculturas e culturas de secreções dos recém-nascidos com suspeita clínica de infecção precoce.Material e Métodos: No período de agosto de 1995 a julho de 1996, foram analisados 69 casos seqüenciais de recém-nascidos com sepse ou síndrome séptica precoce. Os recém-nascidos foram acompanhados para seus desfechos clínicos: crescimento ou não de germe em suas culturas de secreções (sangue, urina, líquor, secreção traqueal ou cateter umbilical). O tamanho mínimo de amostra calculado foi 17 para cada grupo, considerando um nível de significância de 5%.Resultados: Em 17 foi constatado uso de antibiótico previamente ao parto, sendo ampicilina isoladamente ou em associação com gentamicina a opção em 70% das mães. Infecção urinária materna ocorreu em 9 casos (53%), amnionite em 6 casos, em 1 caso observou-se associação de ambos e noutro caso a mãe tinha erisipela. No grupo de mães que não receberam antibiótico (n=52), houve 13 recém-nascidos com culturas positivas; nas 17 mães em tratamento antimicrobiano, nenhum recém-nascido teve culturas positivas (p=0,0164) . O risco relativo de ter cultura positiva se a mãe não tomar antibiótico é 12 vezes maior do que se a mãe tiver recebido antibiótico.Conclusão: O uso de antibióticos antes do parto de recém-nascidos com sepse ou síndrome séptica pode fazer com que as hemoculturas resultem negativas, aumentando a dificuldade diagnóstica da sepse neonatal precoce.J. pediatr. (Rio J.). 1997; 73(3):171-175: infecção neonatal, antibioticoterapia, hemocultura, síndrome séptica, sepse. AbstractObjective: To determine the influence of intrapartum antibiotic therapy on blood and secretion cultures of newborn infants suspected of early-onset sepsis.Material and Methods: From August 1995 through July 1996, 69 sequential newborn infants with early-onset sepsis or septic syndrome were included in the study. All of them were followed for the end point: positivity of blood, urine, CSF, tracheal secretion or umbilical catheter cultures. The sample size was figured out to be 17 for each group, for a significant level of 5%.Results: Seventeen mothers were treated with antibiotic. Ampicillin alone or in association with other drugs was utilized in 70% of them. Urinary tract infection occurred in 9 mothers (53%), ammonites in 6, one mother had both and another one had erysipelas. Thirteen newborn infants had positive cultures in the group whose the mothers had not received antibiotic (n=52), none of the 17 newborn infants delivered by the mothers treated with antibiotic had any positive culture (p=0.0164). The relative risk of positive culture in a septic neonate if the mother is not treated with antibiotic is 12 times higher than if the mother is treated with antibiotic.Conclusion: The use of intrapartum antibiotic in newborn infants with early-onset sepsis or septic syndrome may cause a negativity of cultural exams, increasing the difficulty of the diagnosis of early-onset neonatal sepsis.J. pediatr. (Ri...

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Disinfection of Eyelid Speculums for Retinopathy of Prematurity Examination

Woodman¹

1998

Arch Ophthalmol

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To evaluate the effectiveness of 70% isopropyl alcohol swabs in disinfecting eyelid speculums after examination for retinopathy of prematurity. Methods: Two phases. Phase 1: 46 autoclave-sterilized eyelid speculums randomized into either a cleaned or control group following examination for retinopathy of prematurity. Speculums in the cleaned group were disinfected with a 70% isopropyl alcohol swab while control speculums were not cleaned. Bacterial and fungal cultures were then obtained. Phase 2: 20 autoclavesterilized eyelid speculums inoculated with a clinically relevant dilution of adenovirus serotype 5 or herpes simplex virus type 2. Inoculated speculums were randomized into either a cleaned or control group.

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Neonatal septicaemia.

Cited by 107 publications

References 12 publications

Neonatal Septicaemia in Poor Resource Settings

Neonatal Septicaemia in Poor Resource Settings

The influence of intrapartum antibiotic therapy on the diagnosis of early-onset neonatal sepsis

Disinfection of Eyelid Speculums for Retinopathy of Prematurity Examination

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