Near-infrared Spectroscopy Monitoring of the Collateral Network Prior to, During, and After Thoracoabdominal Aortic Repair: A Pilot Study

Etz, Christian D.; Aspern, Konstantin von; Gudehus, S.; Luehr, Maximilian; Girrbach, Felix; Ender, Joerg; Borger, Michael A.; Mohr, Friedrich W.

doi:10.1016/j.ejvs.2013.08.018

Cited by 82 publications

(58 citation statements)

References 20 publications

(18 reference statements)

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“…Commercial spectroscopy units monitoring animal models indicated ischaemic changes and hypoxia after aortic compression [7]. Human case reports have been found using non-invasive transcutaneous optodes [8], [9]. Those results could provide useful information for patient in surgery where aortic clamping are prone to lead to complications.…”

Section: Introductionmentioning

confidence: 96%

In vivo NIRS monitoring in pig Spinal Cord tissues

Tsiakaka

Terosiet

Romain

et al. 2015

2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)

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Little is known about the processes occurring after Spinal Cord damage. Whether permanent or recoverable, those processes have not been precisely characterized because their mechanism is complex and information on the functioning of this organ are partial. This study demonstrates the feasibility of Spinal Cord activity monitoring using Near Infra-Red Spectroscopy in a pig animal model. This animal has been chosen because of its comparable size and its similarities with humans. In the first step, optical characterization of the Spinal Cord tissues was performed in different conditions using a spectrophotometer. Optical Density was evaluated between 3.5 and 6.5 in the [500; 950] nm range. Secondly, adapted light sources with custom probes were used to observe autonomic functions in the spine. Results on the measured haemodynamics at rest and under stimulation show in real time the impact of a global stimulus on a local section of the Spinal Cord. The photoplethysmogram signal of the Spinal Cord showed low AC-to-DC ratio (below to 1 %).

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Section: Introductionmentioning

confidence: 96%

In vivo NIRS monitoring in pig Spinal Cord tissues

Tsiakaka

Terosiet

Romain

et al. 2015

2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)

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“…NIRS estimates mixed tissue hemoglobin oxygen saturation levels of the arterial, venous, and capillary blood within the field of view [10,11], which allows the oxygen supply-and-demand balance to be evaluated under differing conditions. Similar to what has been done with the cerebrum, several studies have measured spinal cord oxygenation using NIRS directly [12][13][14][15] (via surgical procedure or thin fiber-optic probe placed in the intrathecal or epidural space) or indirectly [16][17][18][19] (via paraspinal muscle oxygenation monitoring, based on the paraspinal collateral network concept) to monitor spinal cord perfusion, but few studies to date have assessed spinal cord autoregulation using this method.…”

Section: Introductionmentioning

confidence: 99%

Spinal cord autoregulation using near-infrared spectroscopy under normal, hypovolemic, and post-fluid resuscitation conditions in a swine model: a comparison with cerebral autoregulation

et al. 2020

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Background: Few studies have investigated spinal cord autoregulation using near-infrared spectroscopy (NIRS). Here, we assessed spinal cord autoregulation under normal, hypovolemic, and post-fluid resuscitation conditions compared with cerebral autoregulation. Methods: Ten pigs (36.1 ± 1.1 kg) were anesthetized with 2.5% isoflurane, before phenylephrine administration at 0.5, 1, 2, and 5 μg kg −1 min −1 in a stepwise fashion at 10-min intervals (baseline), followed by similar administration of sodium nitroprusside (SNP). Hypovolemia was induced by a 600-ml bleed (25% estimated total blood volume). Only phenylephrine was readministered (same protocol). Hypovolemia was reversed by infusing 600 ml hydroxyethyl starch, before readministering phenylephrine and SNP. The relationships between mean arterial pressure (MAP) and cerebral, thoracic, and lumbar spinal cord tissue oxygenation indices (TOIs) were evaluated. Results: Thoracic and lumbar spinal cord TOIs were approximately 15% and 10% lower, respectively, than the cerebral TOI at similar MAPs. The average relationship between MAP and each TOI showed an autoregulatory pattern, but negative correlations were observed in the cerebral TOI during phenylephrine infusion. A 600-ml bleed lowered each relationship < 5% and subsequent fluid resuscitation did not change the relationship. Individual oxygenation responses to blood pressure indicated that the spinal cord is more pressure-passive than the cerebrum. Paradoxical responses (an inverse relationship of tissue oxygenation to MAP) were observed particularly in cerebrum during phenylephrine infusion and were rare in the spinal cord.Conclusions: Spinal cord autoregulation is less robust than cerebral autoregulation and more pressure-dependent. Similar to cerebral oxygenation, spinal cord oxygenation is volume-tolerant but is more sensitive to hypotension.

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“…Monitoring of advanced hemodynamic parameters, such as the stroke volume, cardiac output/index and systemic vascular resistance was achieved with a Vigileo system (Edwards Lifescience, USA) and heart performance was assessed with the transesophageal echocardiography (TEE) throughout the procedure. Regional dermatomal oxygenation at the level of L1 was continuously measured using near-infrared spectroscopic (NIRS) oximetry (INVOS, Covidien, USA) (Etz et al, 2013).…”

Section: Anaesthesiamentioning

confidence: 99%

Juxtarenal Mycotic Aneurysm as a Complication of Acute Exacerbation of Chronic Cholecystitis Treated by Resection and Replacement by a Fresh Allograft

et al. 2016

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We present a case of a female patient with infectious (mycotic) juxtarenal abdominal aneurysm with atypical symptoms beginning as acute exacerbation of chronic cholecystitis. Apart from common antibiotic treatment, the patient successfully underwent resection of the diseased segment and replacement by a fresh allograft in order to reduce the risk of infection of the graft, but with the need of subsequent life-long immunosuppressive therapy. Perioperative monitoring of the spinal cord by near infrared spectroscopy was used to identify possible spinal ischemia. The choice of the fresh allograft was based on our experience supported by review of the literature.

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Near-infrared Spectroscopy Monitoring of the Collateral Network Prior to, During, and After Thoracoabdominal Aortic Repair: A Pilot Study

Abstract: Non-invasive monitoring of CN oxygenation prior to, during, and after thoracoabdominal aortic repair is feasible. Lumbar CN oxygenation levels directly respond to compromise of aortic blood circulation.

Cited by 82 publications

References 20 publications

In vivo NIRS monitoring in pig Spinal Cord tissues

In vivo NIRS monitoring in pig Spinal Cord tissues

Spinal cord autoregulation using near-infrared spectroscopy under normal, hypovolemic, and post-fluid resuscitation conditions in a swine model: a comparison with cerebral autoregulation

Juxtarenal Mycotic Aneurysm as a Complication of Acute Exacerbation of Chronic Cholecystitis Treated by Resection and Replacement by a Fresh Allograft

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