Natürlich vorkommende Cumarin‐Derivate, IX ¹⁾ Über die Inhaltsstoffe der Gattung Gerbera

Abstract

Die Wurzeln mehrerer Gerbera-Arten enthalten die bekaiiiiten Polyine 1 und 2. Aus Gerbera crocea wurden zusatzlich das Acctophenon-Derivat 3 und zwei neue Cumarine (4 und 7) isoliert, deren Strukturen durch spektroskopische Daten sowie durch Synthese geklart werden.

New Chromone, Coumarin, and Coumestan Derivatives fromMutisia acuminatavar.hirsuta

“…After comparing the NMR data of 1 with those of the characteristic coumarins found in the tribe Mutisieae, the 2 broad doublets at ô 7.23 and 7.35 ppm, a triplet at 7.80 ppm together with the broad CH3 singlet at b =2.80 ppm revealed the presence of a 5-methyl-4-O-substituted coumarin C10-unit. These data are in close agreement with some of the 5methylcoumarins which have been isolated from different genera of this tribe (4)(5)(6)(8)(9)(10)(11). The location of the methyl group at C-S was further supported by the long-range coupling between the methyl and the H-6, 7,8 protons.…”

Constituents from Ageratina pichinchensis and Their Inhibitory Effect on Nitric Oxide Production

“…The spectra of 1 H and 13 C-NMR are shown in Figures S11 and S12. Speletone (7) Colorless oil; 1 H-NMR (200 MHz, CDCl 3 ), δ H :8.09 (1H, d, J = 2.4 Hz, H-2), 7.78 (1H, dd, J = 2.2, 7.8 Hz, H6), 6.84 (1H, d, J = 8.4 Hz, H-5), 3.60 (3H, s, OMe), 2.67 (2H, d, J = 7.8 Hz, H-10), 2.33 (3H, s, CH 3 -8), 221 (1H, m, H-11), 0.78 (6H, d, J = 6.8 Hz, CH 3 -12, and CH 3 -13); these data match those in the literature [40]. The spectra of 1 H -NMR are shown in Figure S13.…”

“…From the ethyl acetate extract (leaves), the following were identified: O-methylencecalinol (1) [10,35], encecalin (2) [36,37], eupatoriochromene (3) [38], 6-acetyl-8-hydroxy-2,2dimethylchromene (4) [33,40], 3, 5-diprenyl-4-hydroxyacetophenone (5) [41,42], (+)-β-eudesmol (6) [43,44], espeletone (7) [40], dehydrospeletone (8) [41,42], encecalinol (9) [6,35,45], and 5-acetyl-3β-angeloyloxy-2β-(1-hydroxyisopropyl)-2,3-dihydrobenzofurane (10) [6,10]. In the hydroalcoholic extract (flowers), in addition to some compounds (1, 2, 5, and 6), betuletol 3-O-β-glucoside (11) was identified [46,47].…”

Chemical Composition and Biological Activities of Gerbera anandria

“…A review of the literature indicates that only a few studies have been conducted on Gerbera anandria . Coumarins have been isolated and detected, such as 4-hydroxy-5-methylcoumarin [1], gerberacoumarin [2] and daphnetin 7-methyl ether [3]. Two benzofurans with ethanoyl groups on the pyridine ring were isolated too [4].…”