Natural History of Myocardial Injury After COVID-19 Vaccine–Associated Myocarditis

Alhussein, Muhammad Mustafa; Rabbani, Mohamad; Sarak, Bradley; Dykstra, Steven; Labib, Dina; Flewitt, Jacqueline; Lydell, Carmen; Howarth, Andrew G; Filipchuck, Neil; Kealey, Angela; Colbert, Jillian; Guron, Nita; Kolman, Louis; Merchant, Naeem; Bandali, Murad; Bristow, Mike; White, James A.

doi:10.1016/j.cjca.2022.07.017

Cited by 10 publications

(3 citation statements)

References 37 publications

(44 reference statements)

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“…Однако очаговый субэпикардиальный фиброз регистрируют как среди переболевших (21 %), так и получивших вакцину (5 %, p = 0,04). В то же время при анализе долгосрочных последствий признаков воспаления и дисфункции желудочков у этих лиц не выявлялось [28].…”

Section: последствия вакцинацииunclassified

Pathology of the cardiovascular system in people returning to sports after COVID-19

Sharykin,

Badtieva,

Zholinsky

et al. 2024

jour

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Aim: to summarize the data published in our country and abroad on the diagnosis of cardiac complications after COVID‑19 and to compare it with our own experience of examining such athletes.Materials and methods: open data sources such as eLibrary, Scopus, PubMed etc. were used as a scientific base to achieve the set goal, a meta-analysis of 42 domestic and foreign literature sources was carried out upon the results of post‑COVID changes in athletes. Besides that, the indicators of 11467 athletes, aged from 16 to 45 years, were studied who have been playing for the Moscow national team and who passed in‑depth medical examination on the basis of Sports Medicine Clinic in Moscow Scientific and Practical Center of Medical Rehabilitation, Restorative and Sports Medicine.Results: the prevalence of myocarditis in mild COVID‑19 in athletes does not exceed 1 %, arrhythmia does not exceed 9 %. Classical cardiovascular screening is sufficient for their detection in most cases. If hospitalization is necessary, the risks increase for myocarditis up to 7.2 %, for myocardial infarction up to 4,7 %, for other cardiac complications up to 3–14 % and require advanced diagnostics. For optimal resource management in the healthcare system, a working algorithm for examining athletes returning to trainings after a previous COVID‑19 is proposed.Conclusion: in most cases a classical cardiovascular screening is enough for symptomatic individuals returning to sports trainings after the COVID‑19. However, additional examinations, including loading tests and MRT, are required to find out possible latent ongoing pathology as well to evaluate prospects for the athlete.

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Section: последствия вакцинацииunclassified

Pathology of the cardiovascular system in people returning to sports after COVID-19

Sharykin,

Badtieva,

Zholinsky

et al. 2024

jour

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“…Although no official definition exists for ‘post-COVID-19-Vaccine Syndrome,’ a temporal correlation between receiving a COVID-19 vaccine and the beginning or worsening of a patient’s clinical manifestations is sufficient to make the diagnosis of a COVID-19 vaccine-induced injury when the symptoms are unexplained by other concurrent causes. It should, however, be recognized that there is a significant overlap between the symptoms and features of the long COVID-19 syndrome [ 84 ] and the post-COVID-19-Vaccine Syndrome [ 85 ]. However, a number of clinical features appear to be distinctive of the post-COVID-19 vaccine syndrome; most notably, severe neurological symptoms (particularly small fiber neuropathy) appears to be more common following vaccination [ 86 , 87 , 88 ].…”

Section: Pathophysiologymentioning

confidence: 99%

Strategies for the Management of Spike Protein-Related Pathology

Halma¹,

Plothe²,

Marik³

et al. 2023

Microorganisms

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In the wake of the COVID-19 crisis, a need has arisen to prevent and treat two related conditions, COVID-19 vaccine injury and long COVID-19, both of which can trace at least part of their aetiology to the spike protein, which can cause harm through several mechanisms. One significant mechanism of harm is vascular, and it is mediated by the spike protein, a common element of the COVID-19 illness, and it is related to receiving a COVID-19 vaccine. Given the significant number of people experiencing these two related conditions, it is imperative to develop treatment protocols, as well as to consider the diversity of people experiencing long COVID-19 and vaccine injury. This review summarizes the known treatment options for long COVID-19 and vaccine injury, their mechanisms, and their evidentiary basis.

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“…Although no official definition exists for 'post-Covid-Vaccine Syndrome,' a temporal correlation between receiving a Covid-19 vaccine and the beginning or worsening of a patient's clinical manifestations is sufficient to make the diagnosis of a Covid-19 vaccineinduced injury when the symptoms are unexplained by other concurrent causes. It should however be recognized that there is a significant overlap between the symptoms and features of the long Covid syndrome [167] and the post-Covid-Vaccine Syndrome [168]. However, a number of clinical features appear to be distinctive of the post-Covid vaccine syndrome; most notably, severe neurological symptoms (particularly small fiber neuropathy) appears to be more common following vaccination [169][170][171].…”

Section: Clinical Observationsmentioning

confidence: 99%

Strategies for the Management of Spike Protein-Related Pathology

Halma¹,

Plothe²,

Marik³

et al. 2023

Preprint

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In the wake of the Covid-19 crisis, a need has arisen to prevent and treat two related conditions, Covid vaccine injury and long Covid, both of which have a significant vascular component. Therefore, the management of these conditions require the development of strategies to prevent or dissolve blood clots and restore circulatory health. This review summarizes the evidence on strategies that can be applied to treat both long and vaccine injuries based on similar mechanisms of action.

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Natural History of Myocardial Injury After COVID-19 Vaccine–Associated Myocarditis

Cited by 10 publications

References 37 publications

Pathology of the cardiovascular system in people returning to sports after COVID-19

Pathology of the cardiovascular system in people returning to sports after COVID-19

Strategies for the Management of Spike Protein-Related Pathology

Strategies for the Management of Spike Protein-Related Pathology

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