Natural anti-aging skincare: role and potential

Ahmed, Idris Adewale; Mikail, Maryam Abimbola; Zamakshshari, Nor Hisam; Abdullah, Al-Shwyeh Hussah

doi:10.1007/s10522-020-09865-z

Cited by 102 publications

(95 citation statements)

References 93 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The use of UVB-preventive agents prior to developing skin cancer has been extensively investigated based on these well-established signal transduction markups. Incorporating natural antioxidants from plants and marine extracts into skin care products is becoming an important research focus for anti-aging purposes and the prevention of skin cancer [ 11 ]. Synthetic sunscreen works synergistically with natural antioxidants to maintain redox homeostasis and protect against skin cell damage from UVB radiation [ 12 ].…”

Section: Introductionmentioning

confidence: 99%

Potential Use of Amla (Phyllanthus emblica L.) Fruit Extract to Protect Skin Keratinocytes from Inflammation and Apoptosis after UVB Irradiation

et al. 2021

View full text Add to dashboard Cite

Ultraviolet B (UVB) exposure is the primary risk factor for the deadliest type of skin cancer—melanoma. Incorporating natural antioxidants in skin protection products is currently a favored research theme. For this study, we selected Phyllanthus emblica L. fruit extract (PE) to assess its potential use in dermal protection against UVB-induced keratinocyte inflammation and apoptosis. High-performance liquid chromatography (HPLC) was used to investigate PE’s phytochemical constituents (ascorbic acid, ellagic acid, gallic acid, chlorogenic acid, and quercetin), while ferric reducing antioxidant power (FRAP), oxygen radical absorbance capacity (ORAC), total ROS, OH•, O2•−, and H2O2-scavenging activities were used to determine the antioxidant properties. PE significantly increased the cell viability (MTT assay) and reduced apoptosis (Hoechst staining) in HaCaT cells exposed to UVB (40 mJ/cm2). PE abolished oxidative stress by reducing the production of intracellular ROS, O2•− and H2O2 production. Catalase activity (but not superoxide dismutase or glutathione peroxidase activity) was enhanced in keratinocytes incubated with PE prior to UVB exposure. Western blot analysis suggested that PE inhibited cytochrome c release and inhibited the dysregulation of PI3K/Akt without any impact on p38 activation. PE attenuated the inflammatory response to UVB irradiation by inhibiting AP-1, NF-κB, and the mediator PGE2. Thus, PE is a candidate with great potential for use as an active ingredient in skin care products.

show abstract

Section: Introductionmentioning

confidence: 99%

Potential Use of Amla (Phyllanthus emblica L.) Fruit Extract to Protect Skin Keratinocytes from Inflammation and Apoptosis after UVB Irradiation

et al. 2021

View full text Add to dashboard Cite

show abstract

“…Humectants are water-loving moisturizing agents that draw moisture from the dermis to the stratum corneum and binding water vapor from the environment [ 23 ]. Honey, hyaluronic acid, sorbitol, glycerine, and glycerol are examples of humectants’ moisturizing agents [ 24 ].…”

Section: Natural Antiagingmentioning

confidence: 99%

“…They are potent mutagens and can trigger cancer and immune-mediated disease [ 56 ]. Aloe vera , green tea, coconut oil, grape seeds, and ginger contain phytochemicals that prevent photoaging and skin cancer [ 24 ].…”

Section: Natural Antiagingmentioning

confidence: 99%

The New Challenge of Green Cosmetics: Natural Food Ingredients for Cosmetic Formulations

Dini

Laneri

2021

Molecules

View full text Add to dashboard Cite

Nowadays, much attention is paid to issues such as ecology and sustainability. Many consumers choose "green cosmetics", which are environmentally friendly creams, makeup, and beauty products, hoping that they are not harmful to health and reduce pollution. Moreover, the repeated mini-lock downs during the COVID-19 pandemic have fueled the awareness that body beauty is linked to well-being, both external and internal. As a result, consumer preferences for makeup have declined, while those for skincare products have increased. Nutricosmetics, which combines the benefits derived from food supplementation with the advantages of cosmetic treatments to improve the beauty of our body, respond to the new market demands. Food chemistry and cosmetic chemistry come together to promote both inside and outside well-being. A nutricosmetic optimizes the intake of nutritional microelements to meet the needs of the skin and skin appendages, improving their conditions and delaying aging, thus helping to protect the skin from the aging action of environmental factors. Numerous studies in the literature show a significant correlation between the adequate intake of these supplements, improved skin quality (both aesthetic and histological), and the acceleration of wound-healing. This review revised the main foods and bioactive molecules used in nutricosmetic formulations, their cosmetic effects, and the analytical techniques that allow the dosage of the active ingredients in the food.

show abstract

“…Phytochemicals provide significant health benefits and basic nutrition [1][2][3][4]. The bioactive substances in medicinal plants such as essential oils, polyphenols, and flavonoids have antioxidant and antimicrobial properties, in addition to their chemotherapeutic potential [5][6][7][8]. Efforts to find alternative antioxidants and antibacterial agents from natural sources have been intensified in recent times because of their effectiveness, safety, and efficacy.…”

Section: Introductionmentioning

confidence: 99%

Antioxidant, Antibacterial, and Phytochemical Screening of Ethanolic Crude Extracts of Libyan Peganum harmala Seeds

Allaq

Sidik

Abdul-Aziz

et al. 2021

JPRI

Self Cite

View full text Add to dashboard Cite

Peganum harmala is one of the most famous medicinal plants and natural products commonly used in traditional medicine and extensively spread in Middle and East Asia and North Africa. This study aimed to evaluate the radical scavenging activity of ethanolic crude extracts of P. harmala seeds from Libya using DPPH assay; to determine the minimum inhibitory concentration (MIC) and minimum bactericidal concentrations (MBC) of the P. harmala seeds crude extracts against Gram-negative Salmonella typhi ATCC14028 and Escherichia coli ATCC 25922 and also Gram-positive Bacillus subtilis ATCC 6633 and Staphylococcus aureus ATCC 33591; and to screen the phytochemicals in the ethanolic crude extracts of the Libyan P. harmala seeds using gas chromatography-mass spectrometry (GC-MS). The IC50 value of P. harmala seeds extract was 179.62±7.32 μg/mL. The MIC ranged from 1.95 to 31.25 mg/mL while the MBC ranged from 7.80 to 62.50 mg/mL. The eight compounds identified were harmine, harmaline, leptalorine, hexahydro fluorene, 3-methoxy-6-methyl, 1H-pyrido [3,4-b]indole,2,34,9- tetrahydro-6methoxy-1-methyl, 9,12-octadienoic acid ethyl ester, linoleic acid ethyl ester, 9,12-octadienoic acid (z,z). This study has, therefore, revealed the antixodant and antibacterial efficacy of P. harmala ethanolic extract. Thus, it could be further developed as a substitute for chemical antioxidants and as antibacterials agent.

show abstract

Natural anti-aging skincare: role and potential

Cited by 102 publications

References 93 publications

Potential Use of Amla (Phyllanthus emblica L.) Fruit Extract to Protect Skin Keratinocytes from Inflammation and Apoptosis after UVB Irradiation

Potential Use of Amla (Phyllanthus emblica L.) Fruit Extract to Protect Skin Keratinocytes from Inflammation and Apoptosis after UVB Irradiation

The New Challenge of Green Cosmetics: Natural Food Ingredients for Cosmetic Formulations

Antioxidant, Antibacterial, and Phytochemical Screening of Ethanolic Crude Extracts of Libyan Peganum harmala Seeds

Contact Info

Product

Resources

About