Natural and synthetic functional materials for broad spectrum applications in antimicrobials, antivirals and cosmetics

Abstract

Antimicrobial resistance is the leading cause of burden on healthcare sector. There is scientific challenge of developing new functional material as a platform to prevent and treat viral and microbial infection and cosmetic utility. In material chemistry, there is progress in the development of functional material with advent of nanotechnology with aid of synthetic organic chemistry. The properties and application of material can be changed significantly by modification of the surface functional groups (namely, COOH, HO, NH2OH, SO4,), formation of composite with inorganic material and incorporation of active pharmaceutical agents. In antibacterial application functional material of copper, silver, gold, platinum, tin, iron, cobalt, ruthenium, zinc and pharmaceutical antimicrobial agents found utility in the treatment of bacterial and hospital acquired infection with different resistant strains of microorganisms. In antiviral application many functional materials have been shown to possess remarkable antiviral ability like quantum dots, gold and silver nanoparticles, nanoclusters, carbon dots, graphene oxide and silicon materials. The polymers and dendrimers functionalized with USFDA approved antiviral agent also has potential therapeutic outcomes. Despite their difference in antiviral mechanism and inhibition efficacy, these functional material structures have unique features as potential antiviral candidates. In cosmetic applications functional material based on mica, sericite, fullerene, charcoal, peptides, mineral, lipids, glucocorticoid, nanocellulose hybrid material are extensively used. In this review, we have highlighted early promise and prospects of functional material for cosmetics, antibacterial and antiviral applications, advantages and disadvantages, Patent scenario, current challenges for translation into commercial products.

A Comprehensive Review on Nature and Causes of Deterioration in Fruits and Vegetables

“…Heat treatment methods like blanching and novel techniques like ohmic heating are also utilized to suppress enzymatic activities that lead to spoilage [52]. Natural preservatives, such as essential oils from thyme and oregano, as well as antimicrobial peptides, have shown promise but face challenges in scalability and safety considerations [53]. Alao [2] reported that the most suitable condition for fresh fruits and vegetables in storage is the lowest temperature, which does not cause chilling injury to the fresh produce.…”

Synthesis, Spectral Characterization, Antibacterial and Anticancer Evaluation of Novel Isoniazid based Schiff Base Ligand derived Transition Metal Complexes

“…The remarkable structural features of amino adamantane and thiophene derivatives, which present exciting possibilities for biological uses, have aroused our interest in these compounds [1][2][3]. Amino adamantane derivatives have demonstrated effectiveness against a range of bacteria and fungi, making them promising candidates against infections [4][5][6].…”

Gallium Liquid Metal: Nanotoolbox for Antimicrobial Applications

“…Another study reported that Ga was able to inhibit the growth of Aspergillus fumigatus , a common cause of invasive aspergillosis in immuno­compromised patients . Beyond this, some studies suggest that GaLMs may also be effective against viral infections. , Overall, GaLMs have demonstrated significant potential for treating a broad range of microbial infections including those caused by eukaryotic pathogens such as fungi and viruses. Since GaLMs can interact with both prokaryotic and eukaryotic cells, it is important to fully understand the interactions between GaLMs and mammalian cells.…”