Narrow-band imaging system with magnifying endoscopy for rectal amyloidosis

Hui, Yee Tak; Lam, Ting Wa; Lam, Polly W.Y.; Wu, Wendy; Lam, Wai Ming

doi:10.1016/j.gie.2007.11.049

Gastrointestinal Endoscopy

2008

DOI: 10.1016/j.gie.2007.11.049

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Narrow-band imaging system with magnifying endoscopy for rectal amyloidosis

Yee Tak Hui

Ting Wa Lam

Polly W.Y. Lam

et al.

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Cited by 7 publications

(1 citation statement)

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“…EUS may be helpful for assessing the extent and areas of amyloid deposition, especially in cases presenting with prominent folds and/or a poorly distensible stomach with normal-appearing mucosa [3]. Recently, the usefulness of NBI for diagnosing rectal amyloidosis has been highlighted [5]. In the present case, the erythematous area surrounding the ulcer also appeared grayish-green in color with NBI, indicating clinical applicability of the method in gastric amyloidosis.…”

supporting

confidence: 51%

Endoscopic features of primary amyloidosis of the stomach

et al. 2012

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supporting

confidence: 51%

Endoscopic features of primary amyloidosis of the stomach

et al. 2012

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Amiloidose gastrointestinal

Pereira

Raposo

Carvalheiro

et al. 2013

GE Jornal Português de Gastrenterologia

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Systemic amyloidosis and the gastrointestinal tract

Sattianayagam

Hawkins

Gillmore

2009

Nat Rev Gastroenterol Hepatol

102

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Systemic amyloidosis is characterized by the extracellular deposition of protein in an abnormal fibrillar form. Several different types of amyloidosis exist, each defined by the identity of their respective fibril precursor protein. Among patients with systemic amyloidosis, histological involvement of the gastrointestinal tract is very common but is often subclinical. Conversely, primary diseases of the gastrointestinal tract can cause systemic amyloidosis; for example, AA amyloidosis can occur secondary to IBD. The presence and pattern of gastrointestinal symptoms varies substantially, not only between the different types of amyloidosis but also within them. Typical clinical presentations, most of which are nonspecific, include macroglossia, hemorrhage, motility disorders, disturbance of bowel habit and malabsorption. Endoscopic and radiological features are also nonspecific, with the small intestine most commonly affected. Currently, the aim of therapy for amyloidosis is to slow amyloid formation by reducing the abundance of the fibril precursor protein. No specific treatments for the gastrointestinal symptoms of systemic amyloidosis are available; however, case reports and small published series encourage nutritional support for patients with motility disorders and pharmacological agents for treatment of diarrhea. Surgical procedures should be contemplated only in an emergency setting because of the risk of decompensation of organs affected by amyloid deposition.

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Narrow-band imaging system with magnifying endoscopy for rectal amyloidosis

Cited by 7 publications

References 6 publications

Endoscopic features of primary amyloidosis of the stomach

Endoscopic features of primary amyloidosis of the stomach

Amiloidose gastrointestinal

Systemic amyloidosis and the gastrointestinal tract

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