Nanotechnology-Based Approaches in Pediatric Parasitic Infections

Nawaz, Muhammad

doi:10.1055/s-0037-1603497

Cited by 6 publications

(4 citation statements)

References 64 publications

(37 reference statements)

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“…After the vast literature consulted, we can conclude that the growth in the development and production of nanoparticles worldwide has been exponential, mainly due to their excellent physicochemical properties [181,182]. In this era, the inventors, producers and consumers of almost all sectors have the opportunity to link nanotechnology to their work.…”

Section: Discussionmentioning

confidence: 99%

Targeting Polymeric Nanobiomaterials as a Platform for Cartilage Tissue Engineering

García-Couce

Almirall

Fuentes

et al. 2019

CPD

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Articular cartilage is a connective tissue structure that is found in anatomical areas that are important for the movement of the human body. Osteoarthritis is the ailment that most often affects the articular cartilage. Due to its poor intrinsic healing capacity, damage to the articular cartilage is highly detrimental and at present the reconstructive options for its repair are limited. Tissue engineering and the science of nanobiomaterials are two lines of research that together can contribute to the restoration of damaged tissue. The science of nanobiomaterials focuses on the development of different nanoscale structures that can be used as carriers of drugs / cells to treat and repair damaged tissues such as articular cartilage. This review article is an overview of the composition of articular cartilage, the causes and treatments of osteoarthritis, with a special emphasis on nanomaterials as carriers of drugs and cells, which reduce inflammation, promote the activation of biochemical factors and ultimately contribute to the total restoration of articular cartilage.

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Section: Discussionmentioning

confidence: 99%

Targeting Polymeric Nanobiomaterials as a Platform for Cartilage Tissue Engineering

García-Couce

Almirall

Fuentes

et al. 2019

CPD

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“…For the treatment of leishmaniasis, nanotechnology-based drug delivery systems have been developed to minimize toxicity while maintaining therapeutic efficacy [ 25 ]. Moreover, nanotechnology presents innovative solutions for administering drugs to pediatric patients affected by malaria, leishmaniasis, toxoplasmosis, and schistosomiasis [ 171 ].…”

Section: Infectious Disease Management and Treatmentmentioning

confidence: 99%

Exploring the Potential of Nanotechnology in Pediatric Healthcare: Advances, Challenges, and Future Directions

Omidian

Mfoafo

2023

Pharmaceutics

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The utilization of nanotechnology has brought about notable advancements in the field of pediatric medicine, providing novel approaches for drug delivery, disease diagnosis, and tissue engineering. Nanotechnology involves the manipulation of materials at the nanoscale, resulting in improved drug effectiveness and decreased toxicity. Numerous nanosystems, including nanoparticles, nanocapsules, and nanotubes, have been explored for their therapeutic potential in addressing pediatric diseases such as HIV, leukemia, and neuroblastoma. Nanotechnology has also shown promise in enhancing disease diagnosis accuracy, drug availability, and overcoming the blood–brain barrier obstacle in treating medulloblastoma. It is important to acknowledge that while nanotechnology offers significant opportunities, there are inherent risks and limitations associated with the use of nanoparticles. This review provides a comprehensive summary of the existing literature on nanotechnology in pediatric medicine, highlighting its potential to revolutionize pediatric healthcare while also recognizing the challenges and limitations that need to be addressed.

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“…Nanotechnology has inspired the design of diverse nanoscale materials to fulfill the growing material requirements for environmental, biological, and medical applications [1][2][3][4][5][6]. Environmental pollution has become a serious global concern due to the rapid increase in population and industries.…”

Section: Introductionmentioning

confidence: 99%

Hydrothermal Synthesis of β-Nb2ZnO6 Nanoparticles for Photocatalytic Degradation of Methyl Orange and Cytotoxicity Study

Almofty

Nawaz

Qureshi

et al. 2022

IJMS

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β-Nb2ZnO6 nanoparticles were synthesized by a hydrothermal process and calcined at two temperatures, 500 °C and 700 °C, and assigned as A and B, respectively. X-ray diffraction, together with transmission electron microscopy, revealed that the β-Nb2ZnO6 nanoparticles calcined at 700 °C (B) were more crystalline than the β-Nb2ZnO6 calcined at 500 °C (A) with both types of nanoparticles having an average size of approximately 100 nm. The physiochemical, photocatalytic, and cytotoxic activities of both types of β-Nb2ZnO6 nanoparticles (A and B) were examined. Interestingly, the photodegradation of methyl orange, used as a standard for environmental pollutants, was faster in the presence of the β-Nb2ZnO6 nanoparticles calcined at 500 °C (A) than in the presence of those calcined at 700 °C (B). Moreover, the cytotoxicity was evaluated against different types of cancer cells and the results indicated that both types of β-Nb2ZnO6 nanoparticles (A and B) exhibited high cytotoxicity against MCF-7 and HCT116 cells but low cytotoxicity against HeLa cells after 24 and 48 h of treatment. Overall, both products expressed similar EC50 values on tested cell lines and high cytotoxicity after 72 h of treatment. As a photocatalyst, β-Nb2ZnO6 nanoparticles (A) could be utilized in different applications including the purification of the environment and water from specific pollutants. Further biological studies are required to determine the other potential impacts of utilizing β-Nb2ZnO6 nanoparticles in the biomedical application field.

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Nanotechnology-Based Approaches in Pediatric Parasitic Infections

Cited by 6 publications

References 64 publications

Targeting Polymeric Nanobiomaterials as a Platform for Cartilage Tissue Engineering

Targeting Polymeric Nanobiomaterials as a Platform for Cartilage Tissue Engineering

Exploring the Potential of Nanotechnology in Pediatric Healthcare: Advances, Challenges, and Future Directions

Hydrothermal Synthesis of β-Nb2ZnO6 Nanoparticles for Photocatalytic Degradation of Methyl Orange and Cytotoxicity Study

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